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Protein Alignment CHIA and Cht10

DIOPT Version :9

Sequence 1:	NP_970615.2	Gene:	CHIA / 27159	HGNCID:	17432	Length:	476	Species:	Homo sapiens
Sequence 2:	NP_001036422.1	Gene:	Cht10 / 3355116	FlyBaseID:	FBgn0250907	Length:	2286	Species:	Drosophila melanogaster

Alignment Length:	481	Identity:	179/481 - (37%)
Similarity:	249/481 - (51%)	Gaps:	48/481 - (9%)

- Green bases have known domain annotations that are detailed below.

Human    20 SAYQLTCYFTNWAQYRPGLGRFMPDNIDPCLCTHLIYAFAGRQNNEI---TTIEWNDV--TLYQA 79
            |.|::.|||||||.||.|:|||.||:|:..||||:||.||....:|:   |...|.||  ..|..
  Fly   963 SHYKVICYFTNWAWYRKGIGRFTPDDINTELCTHVIYGFAVLDYSELVLRTHDSWADVENNFYTR 1027

Human    80 FNGLKNKNSQLKTLLAIGGWNFGTA-PFTAMVSTPENRQTFITSVIKFLRQYEFDGLDFDWEYP- 142
            ...||:|.  :|..||:||||.... .::.:|.:|..|..|:...::|:.:|.|:|||.|||||
  Fly  1028 VTSLKSKG--IKVSLALGGWNDSQGDKYSRLVRSPMARSRFVRHALEFIEKYGFEGLDLDWEYPV 1090

Human   143 -----GSRGSPPQDKHLFTVLVQEMREAFEQEAKQINKPR-LMVTAAVAAGISNIQSGYEIPQLS 201
                 .::|| .::|..||..|||:.|||        :|| ||::.||:.....|.:||:|||||
  Fly  1091 CWQTECNKGS-TEEKDGFTAWVQELSEAF--------RPRGLMLSTAVSPSRKIIDAGYDIPQLS 1146

Human   202 QYLDYIHVMTYDLHGSWEGYTGENSPLYKYPTDTGSNAYLNVDYVMNYWKDNGAPAEKLIVGFPT 266
            :|.|:|.|||||.||.|:..||..:|||.:|.|  ...|.||:|.:|||.:.|||::||::|.|.
  Fly  1147 RYFDWIAVMTYDFHGHWDKKTGHVAPLYHHPDD--DFEYFNVNYSINYWMEKGAPSQKLVMGIPL 1209

Human   267 YGHNFILSNPSNTGIGAPTSGAGPAGPYAKESGIWAYYEICTFLKNGATQGWDAPQEV-----PY 326
            ||.:|.|.|.:::|:.|.....|.||.:.:.:|..||||||..:..   |||....:.     ||
  Fly  1210 YGQSFTLENTNSSGLNAKAPAPGEAGEFTRAAGFLAYYEICERVNR---QGWQVVHDEFGRMGPY 1271

Human   327 AYQGNVWVGYDNIKSFDIKAQWLKHNKFGGAMVWAIDLDDFTGTFCNQGKFPLISTLKKALGLQS 391
            ||:|..||.||:......|:..::..|.||.||||:|||||... |..|..||::.:...|....
  Fly  1272 AYKGTQWVSYDSPDMVRKKSLLVRSLKLGGGMVWALDLDDFKNR-CGNGVHPLLTEIHNVLKDPP 1335

Human   392 ASCTAPAQPIEPITAAPSGSGNGSGSSSSGGSSGGSGFCAVRANGLYPVANNRNAFWHCV---NG 453
            :....|.    ||...|:   ...|.......|.|.|........:.....|.......:   |.
  Fly  1336 SLMEIPG----PIETTPT---EYPGMEEEIHESNGEGPEVQPIEAVMQTCENEGEEHEGILDPNH 1393

Human   454 VTYQQNCQA---GLVFDTSCDCCNWA 476
            |..::|.:|   ...|...|...|||
  Fly  1394 VLEEENIEATEMATEFKIICYFTNWA 1419

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.