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Protein Alignment CHIA and Cht11

DIOPT Version :9

Sequence 1:	NP_970615.2	Gene:	CHIA / 27159	HGNCID:	17432	Length:	476	Species:	Homo sapiens
Sequence 2:	NP_572361.1	Gene:	Cht11 / 31630	FlyBaseID:	FBgn0029913	Length:	432	Species:	Drosophila melanogaster

Alignment Length:	400	Identity:	121/400 - (30%)
Similarity:	191/400 - (47%)	Gaps:	50/400 - (12%)

- Green bases have known domain annotations that are detailed below.

Human    13 ILNLQLGSAY----QLTCYFTNWAQYRPGLGRFMPDNIDPCLCTHLIYAFAGRQN------NEIT 67
            :|.:|.|..:    :|.||:.:...:...|.....|     ||||:....|...|      :.:.
  Fly    54 LLGIQTGEVHKVGQRLVCYYASDGTHNLSLLDVPGD-----LCTHINIGPATLDNATIVLPDTLR 113

Human    68 TIEWNDVTLYQAFNGLKNKNSQLKTLLAIGGWNFGTAPFTAMVSTPENRQTFITSVIKFLRQY-E 131
            .:..||...::|      .:.|:..||.|||.:.|.: |..||:....|:.|:.|:.:.||.| .
  Fly   114 QVLQNDTRSFRA------AHPQVHLLLWIGGADSGRS-FALMVANHAMRKLFLRSLREILRTYPS 171

Human   132 FDGLDFDWEYPGSRGSPPQDKHLFTVLVQEMREAFEQEAKQINKPRLMVTAAVAAGISNIQSGYE 196
            .||:|.|||:|.:...  :..|| :.|:.|:|..:.:| |:.|.   :::.||||........|:
  Fly   172 LDGIDLDWEFPSAYDR--ERMHL-SQLLYEIRTEWRRE-KRTND---ILSLAVAAPEGIAFYAYD 229

Human   197 IPQLSQYLDYIHVMTYDLHGSWEG--YTGENSPLYKYPTDTGSNAYLNVDYVMNYWKDNGAPAEK 259
            |.:::.|.||:::|:||.|...|.  :||.|:|||....:....|..|::|.:.:|..:|...::
  Fly   230 IREINLYADYVNLMSYDFHFYREDTPFTGLNAPLYARSQERSLMATFNINYTVQWWLKSGLEPQR 294

Human   260 LIVGFPTYGHNFILSNPSNTGIGAPTSGAGPAGPYAKESGIWAYYEIC----TFLKNGATQGWDA 320
            |:||.|||||:|.|.||.|..||||.||.|..|    :.|.....|.|    .|.|...:  :||
  Fly   295 LVVGLPTYGHSFTLVNPLNHRIGAPASGYGKCG----QLGFTTLTETCECVTKFFKPNLS--YDA 353

Human   321 PQEVPYAYQGNVWVGYDNIKSFDIKAQWLKHNKFGGAMVWAIDLDDFTGT--------FCNQGKF 377
            ....||......|:.|:|..|...||.::|....||.||::::.||...:        :..:..|
  Fly   354 ESCSPYLSALQEWISYENQTSIACKANYVKSLNLGGVMVFSLNTDDLKNSCSIMPNLKYSEKPVF 418

Human   378 PLISTLKKAL 387
            ||...:|..|
  Fly   419 PLTQAIKDIL 428

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.