Protein Alignment HSPB7 and Hsp27

DIOPT Version :10

• Sequence 1: NP_001336611.1
• Gene: HSPB7 / 27129
• HGNCID: 5249
• Length: 245
• Species: Homo sapiens
• Sequence 2: NP_524000.1
• Gene: Hsp27 / 39078
• FlyBaseID: FBgn0001226
• Length: 213
• Species: Drosophila melanogaster
• Alignment Length: 210
• Identity: 49/210 - (23%)
• Similarity: 72/210 - (34%)
• Gaps: 66/210 - (31%)

Human    47 WGHL---DWVWAHVSRSSQRGLPGGGGIGA-DLGRKGRIWRGQQRPLTATWAEQRAWPPLRMAST 107
            ||||   |:               |.|:.| ||....|                     |.:.:|
  Fly    21 WGHLLEDDF---------------GFGVHAHDLFHPRR---------------------LLLPNT 49

Human   108 LAQGKDPPMEKALSMFSDDFGSFMRPHSEPLAFPARPGGAGN--IKTLG-DAYEFAVDVRDFSPE 169
            |..|:            ..:..:.|.|........|..|..|  :..:| |.::..:||..|.|.
  Fly    50 LGLGR------------RRYSPYERSHGHHNQMSRRASGGPNALLPAVGKDGFQVCMDVSQFKPN 102

Human   170 DIIVTTSNNHIEVRA---EKLAADGTVMNTFAHKCQLPEDVDPTSVTSALREDGSLTIRARRHPH 231
            ::.|...:|.:.|..   |:....|.:...|..|..||:..||..|.|.:..||.||::|...|.
  Fly   103 ELTVKVVDNTVVVEGKHEEREDGHGMIQRHFVRKYTLPKGFDPNEVVSTVSSDGVLTLKAPPPPS 167

Human   232 TE--------HVQQT 238
            .|        .:|||
  Fly   168 KEQAKSERIVQIQQT 182

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HSPB7	NP_001336611.1	ACD_HspB7_like	148..228	CDD:107234	25/85 (29%)
Hsp27	NP_524000.1	metazoan_ACD	86..163	CDD:107247	23/76 (30%)