DRSC/TRiP Functional Genomics Resources

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Protein Alignment DKK2 and NimB4

DIOPT Version :9

Sequence 1:NP_055236.1 Gene:DKK2 / 27123 HGNCID:2892 Length:259 Species:Homo sapiens
Sequence 2:NP_788046.1 Gene:NimB4 / 34814 FlyBaseID:FBgn0028542 Length:448 Species:Drosophila melanogaster


Alignment Length:210 Identity:43/210 - (20%)
Similarity:66/210 - (31%) Gaps:81/210 - (38%)


- Green bases have known domain annotations that are detailed below.


Human    81 DKECE-VGRYCHSPHQG--SSACMVCRRKK-----------KRCHRDGMCCPSTRCNNGICIPVT 131
            |||.: ||....:|:..  ...|...||.:           :||..:|.|....:|   :|.  |
  Fly   104 DKEVKIVGNSSTNPYMNVIEVCCKGWRRYEYDWSQCVPDCGERCQENGFCVAGGKC---VCF--T 163

Human   132 ESILTPHIPALDGTRHRDRNHGHYSNHDLGWQNLGRPHTKMSHIKGHEGDPCLRSSDC------- 189
            :.:|                  :|.|:.:....||.||.:           |..:..|       
  Fly   164 DFVL------------------NYRNNCVPTCPLGCPHGR-----------CYLNGTCQCDKGYE 199

Human   190 IEGFCCARHFWTKICKPVLHQGEVCTKQRKKGSHGLEIFQRCDCAKG----------LSCK--VW 242
            ::|   :|.|....|.......|||.:..|           |.||:|          |.|:  ..
  Fly   200 LDG---SRKFCQPQCNATCGHNEVCLEPGK-----------CSCAEGYTRGLRESAALGCQPICI 250

Human   243 KDATYSSKARLHVCQ 257
            .|..|....|.:.|:
  Fly   251 PDCGYGHCVRPNECE 265

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DKK2NP_055236.1 Dickkopf_N 78..128 CDD:282549 14/60 (23%)
DKK-type Cys-1 78..127 14/59 (24%)
DKK-type Cys-2 183..256 19/91 (21%)
NimB4NP_788046.1 None


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1218
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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