DRSC/TRiP Functional Genomics Resources

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Protein Alignment SDCBP2 and X11Lbeta

DIOPT Version :10

Sequence 1:NP_536737.3 Gene:SDCBP2 / 27111 HGNCID:15756 Length:292 Species:Homo sapiens
Sequence 2:NP_727440.3 Gene:X11Lbeta / 31997 FlyBaseID:FBgn0052677 Length:2139 Species:Drosophila melanogaster


Alignment Length:154 Identity:36/154 - (23%)
Similarity:71/154 - (46%) Gaps:2/154 - (1%)


- Green bases have known domain annotations that are detailed below.


Human   130 LFVQLVQANTPASLVGLRFGDQLLQIDGRDCAGWSSHKAHQVVKKASGDKIV--VVVRDRPFQRT 192
            :...|:.:...|....|..||||:.|:|....|.........:|......:|  .||...|....
  Fly  1986 VIANLMSSGAAARCGQLNIGDQLIAINGLSLVGLPLSTCQTYIKNTKNQTVVKFTVVPCAPVVEV 2050

Human   193 VTMHKDSMGHVGFVIKKGKIVSLVKGSSAARNGLLTNHYVCEVDGQNVIGLKDKKIMEILATAGN 257
            .....::...:||.::.|.|.||::|..|.|.|:...|.:.|::.|:|:.:..:||:.:|||:..
  Fly  2051 KIKRPETKYQLGFSVQNGVICSLLRGGIAERGGVRVGHRIIEINNQSVVAVPHEKIVNLLATSVG 2115

Human   258 VVTLTIIPSVIYEHMVKKLPPVLL 281
            .:.:..:|:.::..:..:..|:.:
  Fly  2116 EILMKTMPTSMFRLLTGQENPIYI 2139

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SDCBP2NP_536737.3 PDZ1_syntenin-like 107..185 CDD:467204 13/56 (23%)
PDZ2_syntenin-like 187..264 CDD:467256 20/76 (26%)
X11LbetaNP_727440.3 PTB_X11 1770..1924 CDD:269919
PDZ1_APBA1_3-like 1957..2042 CDD:467203 12/55 (22%)
PDZ2_APBA1_3-like 2046..2123 CDD:467255 20/76 (26%)
Blue background indicates that the domain is not in the aligned region.

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