Protein Alignment GK and gk

DIOPT Version :10

• Sequence 1: XP_011543793.1
• Gene: GK / 2710
• HGNCID: 4289
• Length: 587
• Species: Homo sapiens
• Sequence 2: XP_012811696.1
• Gene: gk / 100038285
• XenbaseID: XB-GENE-961541
• Length: 562
• Species: Xenopus tropicalis
• Alignment Length: 588
• Identity: 476/588 - (80%)
• Similarity: 515/588 - (87%)
• Gaps: 30/588 - (5%)

Human     1 MAASKKAVLGPLVGAVDQGTSSTRFLVFNSKTAELLSHHQVEIKQEFPREGWVEQDPKEILHSVY 65
            ||||.:.:|||||||:|||||||||||||:|||||||||||||||:||:||||||||||||.|||
 Frog     1 MAASNRVILGPLVGAIDQGTSSTRFLVFNAKTAELLSHHQVEIKQKFPKEGWVEQDPKEILQSVY 65

Human    66 ECIEKTCEKLGQLNIDISNIKAIGVSNQRETTVVWDKITGEPLYNAVAAPVSPGPSVPVAVVPSG 130
            ||:|||||||.||||||:|||||||||||||||||||.|||||||||
 Frog    66 ECVEKTCEKLTQLNIDITNIKAIGVSNQRETTVVWDKTTGEPLYNAV------------------ 112

Human   131 SSVPAPGTSSVWLDLRTQSTVESLSKRIPG-NNNFVKSKTGLPLSTYFSAVKLRWLLDNVRKVQK 194
                      ||||||||||||.|.||||| |.||.||:|||||||||||||:|||||||.:::.
 Frog   113 ----------VWLDLRTQSTVERLLKRIPGKNKNFFKSRTGLPLSTYFSAVKIRWLLDNVEEIRH 167

Human   195 AVEEKRALFGTIDSWLIWSLTGGVNGGVHCTDVTNASRTMLFNIHSLEWDKQLCEFFGIPMEILP 259
            ||.|.||:|||:|||:||||||..|||||||||||||||||||||:||||.:||:||.||||:||
 Frog   168 AVSEGRAMFGTVDSWIIWSLTGAKNGGVHCTDVTNASRTMLFNIHTLEWDTELCQFFDIPMELLP 232

Human   260 NVRSSSEIYGLMKISHSVKAGALEGVPISGCLGDQSAALVGQMCFQIGQAKNTYGTGCFLLCNTG 324
            .|||||||||||||..|:|:|||.||||||||||||||||||||||.||||||||||||||||||
 Frog   233 KVRSSSEIYGLMKICPSLKSGALTGVPISGCLGDQSAALVGQMCFQDGQAKNTYGTGCFLLCNTG 297

Human   325 HKCVFSDHGLLTTVAYKLGRDKPVYYALEGSVAIAGAVIRWLRDNLGIIKTSEEIEKLAKEVGTS 389
            .|.|.|:||||||||||||||||..|||||||||||||:|||||||||:||:||:||||.|||||
 Frog   298 SKPVLSEHGLLTTVAYKLGRDKPACYALEGSVAIAGAVVRWLRDNLGIVKTTEEVEKLAAEVGTS 362

Human   390 YGCYFVPAFSGLYAPYWEPSARGIICGLTQFTNKCHIAFAALEAVCFQTREILDAMNRDCGIPLS 454
            |||||||||||||||||||||||||||||||||:.||||||||||||||||||||||:||||||:
 Frog   363 YGCYFVPAFSGLYAPYWEPSARGIICGLTQFTNRNHIAFAALEAVCFQTREILDAMNKDCGIPLN 427

Human   455 HLQVDGGMTSNKILMQLQADILYIPVVKPSMPETTALGAAMAAGAAEGVGVWSLEPEDLSAVTME 519
            .|||||||||||||||||||||.|||||||||||||||||||||||||||||||.|.||:|||.|
 Frog   428 QLQVDGGMTSNKILMQLQADILCIPVVKPSMPETTALGAAMAAGAAEGVGVWSLNPGDLTAVTCE 492

Human   520 RFEPQINAEESEIRYSTWKKAVMKSMGWVTTQSPE-SGDPSIFCSLPLGFFIVSSMVMLIGARYI 583
            |||||||.||||.||:.|||||||||||.:.:... :||.||||||||||:||||||:||||:||
 Frog   493 RFEPQINPEESEFRYARWKKAVMKSMGWESAEPTNGNGDCSIFCSLPLGFYIVSSMVLLIGAKYI 557

Human   584 SGI 586
            ||:
 Frog   558 SGL 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GK	XP_011543793.1	ASKHA_NBD_FGGY_GK1-3-like	11..544	CDD:466802	439/533 (82%)
gk	XP_012811696.1	ASKHA_NBD_FGGY_GK1-3-like	11..517	CDD:466802	439/533 (82%)