Protein Alignment FOXP1 and fd102C

DIOPT Version :10

• Sequence 1: NP_001231739.1
• Gene: FOXP1 / 27086
• HGNCID: 3823
• Length: 693
• Species: Homo sapiens
• Sequence 2: NP_651951.1
• Gene: fd102C / 43843
• FlyBaseID: FBgn0039937
• Length: 599
• Species: Drosophila melanogaster
• Alignment Length: 464
• Identity: 89/464 - (19%)
• Similarity: 152/464 - (32%)
• Gaps: 168/464 - (36%)

Human   331 HALDDRSTAQCRVQMQVVQQLELQL---AKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLS 392
            :.|....|:|.:.....::|..|||   |.:.|||:               .||
  Fly    36 YPLGTTRTSQAQSTTMTLEQYRLQLYNYALNIERLR---------------CPQ----------- 74

Human   393 KSASEASPQSLPHTPTTP-----TAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADI 452
            ...:..|..|.|....:|     :..|      |||....::.|:                 :..
  Fly    75 YGGTGGSGASAPWLHLSPYGHHGSGSL------PSVNRMAALSTI-----------------SLF 116

Human   453 AQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKGAIRTNL 517
            .|.|..::..|.:|..:|..||..|||.|.:.:|.|::||.:....:.|||.....|:.:||.||
  Fly   117 PQTQRIFQPEEPKPQHSYIGLIAMAILSSTDMKLVLSDIYQYILDNYPYFRSRGPGWRNSIRHNL 181

Human   518 SLHKCFI---RVEDEFGSFWTV---DDEEFKRGRHIQRGRPRK---------------------- 554
            ||:.|||   |..:..|.:|.:   :.|:|::|...:|...||
  Fly   182 SLNDCFIKSGRSANGKGHYWAIHPANMEDFRKGDFRRRKAQRKVRKHMGLSVDDASTDSPSPPPL 246

Human   555 ------------------------------------------YCPDE-----------NFDELVA 566
                                                      |.|.:           |.|:.:
  Fly   247 DLTTPPPPSSQSALQLSALGYPYHQHYIGQFFNRSSAPGMTHYSPPDPALLMQRQEANNLDQTI- 310

Human   567 HNPSLIKNMQSSHAYCTPLNAALQASMA----ENSIPLYTTASMGNPTLGNLASAIREELNGAME 627
             .|:.::...|.|.:...:|:....::|    :.....:..||:..|.: .:...:.|:...::.
  Fly   311 -QPTQLQQPHSHHQHFAYINSTTTTTIANMFSQTRKRQFDVASLLAPDV-QIVDIVSEDQESSVT 373

Human   628 HTNSNESDSSPGRSPMQAVHPVHVK-----------EEPLDPEEAEGPLSL---VTTANHS--PD 676
            .|.|       .|:..|..|.|..|           |:|:...:.:..:.:   |...:.|  ||
  Fly   374 PTTS-------ARTTTQTHHTVITKQTIHREVVLGLEKPVQDADIDADIDVEVNVDVVDDSIIPD 431

Human   677 FDHDRDYED 685
            .|...|.||
  Fly   432 TDSYTDGED 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FOXP1	NP_001231739.1	FOXP-CC	302..369	CDD:465036	11/40 (28%)
		FH_FOX	464..545	CDD:469596	30/86 (35%)
fd102C	NP_651951.1	FH_FOXQ2-like	129..223	CDD:410809	32/93 (34%)