Protein Alignment FOXP1 and foxo

DIOPT Version :10

• Sequence 1: NP_001231739.1
• Gene: FOXP1 / 27086
• HGNCID: 3823
• Length: 693
• Species: Homo sapiens
• Sequence 2: NP_650330.3
• Gene: foxo / 41709
• FlyBaseID: FBgn0038197
• Length: 622
• Species: Drosophila melanogaster
• Alignment Length: 347
• Identity: 84/347 - (24%)
• Similarity: 128/347 - (36%)
• Gaps: 97/347 - (27%)

Human   392 SKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQ 456
            :::.|...|...|.....||..|..        |..|...:.|     .|.... |.:|:.|:..
  Fly    38 TRARSNTWPCPRPENFVEPTDELDS--------TKASNQQLAP-----GDSQQA-IQNANAAKKN 88

Human   457 EFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFR-----RNAATWKGAIRTN 516
            ...:||...  .:||.||..||..:.:|:|||::||.|..:...||:     .::|.||.:||.|
  Fly    89 SSRRNAWGN--LSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHN 151

Human   517 LSLHKCFIRVEDEFG---SFWTVDDEEFKRGRHI--------------QRGRPRKY--------- 555
            ||||..|:||::| |   |.|.:.:.|.|.|:.:              :|||.:|.
  Fly   152 LSLHNRFMRVQNE-GTGKSSWWMLNPEAKPGKSVRRRAASMETSRYEKRRGRAKKRVEALRQAGV 215

Human   556 --------CPDENFDELVAH--------------NPSLIKNMQSSHAYC---TPLNAALQASMAE 595
                    .|..:..|.:.|              :|...:...|:.:.|   :|:.|  |....:
  Fly   216 VGLNDATPSPSSSVSEGLDHFPESPLHSGGGFQLSPDFRQRASSNASSCGRLSPIRA--QDLEPD 278

Human   596 NSIPLYTTASMGNPTLGNLASAIREELNGAM--EHTNSNESD----------SSPGRSPMQAVHP 648
            ...|:    ...|.|:....:...|||.|.|  |.|..|:..          |.|...|.|.  |
  Fly   279 WGFPV----DYQNTTMTQAHAQALEELTGTMADELTLCNQQQQGFSAASGLPSQPPPPPYQP--P 337

Human   649 VH----VKEEPLDPEEAEGPLS 666
            .|    .:::...|....||.|
  Fly   338 QHQQAQQQQQQQSPYALNGPAS 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FOXP1	NP_001231739.1	FOXP-CC	302..369	CDD:465036
		FH_FOX	464..545	CDD:469596	34/88 (39%)
foxo	NP_650330.3	FH_FOXO	96..175	CDD:410806	32/81 (40%)