Protein Alignment FOXP1 and Foxp1

DIOPT Version :10

• Sequence 1: NP_001231739.1
• Gene: FOXP1 / 27086
• HGNCID: 3823
• Length: 693
• Species: Homo sapiens
• Sequence 2: XP_038963306.1
• Gene: Foxp1 / 297480
• RGDID: 1308669
• Length: 733
• Species: Rattus norvegicus
• Alignment Length: 749
• Identity: 641/749 - (85%)
• Similarity: 659/749 - (87%)
• Gaps: 72/749 - (9%)

Human     1 MMQESGTETKSNGSAIQNGSGGSNHLLECGGLREGRSNGETPAVDIGAADLAHAQQQQQQ----- 60
            ||||||:|.|||||.|||||.|.|||||||.||:.|||||.||||:|||||||.||||||
  Rat     1 MMQESGSEAKSNGSTIQNGSSGGNHLLECGTLRDTRSNGEAPAVDLGAADLAHVQQQQQQKNVNE 65

Human    61 -----------------ALQVARQLLL--------------------------------QQQQQQ 76
                             ||||||||||                                ||||||
  Rat    66 DRSPFQTQGLKDILETGALQVARQLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 130

Human    77 QVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQ 141
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   131 QVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQ 195

Human   142 QLQEFYKKQQEQLQLQLLQQQHAGKQPKE--QQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGL 204
            |||||||||||||||||||||||||||||  ||||||||||||||||||||||||||||||||||
  Rat   196 QLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGL 260

Human   205 LTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSL 269
            ||||||||||||||||||||||||||||||||||||||||||:||||||||:|||||||||||||
  Rat   261 LTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGSNHSSLDLTSTCVSSSAPSKTSL 325

Human   270 IMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALD 334
            ||||||||||||||||||||||||||||||||||||||||||||||||:||.:||||||||||||
  Rat   326 IMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCDDFPAFLKHLNSEHALD 390

Human   335 DRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEAS 399
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   391 DRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEAS 455

Human   400 PQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEV 464
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   456 PQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEV 520

Human   465 RPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKGAIRTNLSLHKCFIRVEDE 529
            ||||||||||||||||||||||||||||||||||||||||||||||.|:|.||||||||:|||:.
  Rat   521 RPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENV 585

Human   530 FGSFWTVDDEEFKRGRHIQRGRPRKYCPDENFDELVAHNPSLIKNMQSSHAYCTPLNAALQASMA 594
            .|:.||||:.||      |:.||:|          ::.||||||||||.||||||||||||||||
  Rat   586 KGAVWTVDEVEF------QKRRPQK----------ISGNPSLIKNMQSGHAYCTPLNAALQASMA 634

Human   595 ENSIPLYTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPE 659
            ||||||||||||||||||:|||||||||||||||||||||||||||||||||||:||||||||||
  Rat   635 ENSIPLYTTASMGNPTLGSLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPIHVKEEPLDPE 699

Human   660 EAEGPLSLVTTANHSPDFDHDRDYEDEPVNEDME 693
            ||||||||||||||||||||||||||||||||||
  Rat   700 EAEGPLSLVTTANHSPDFDHDRDYEDEPVNEDME 733

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FOXP1	NP_001231739.1	FOXP-CC	302..369	CDD:465036	63/66 (95%)
		FH_FOX	464..545	CDD:469596	67/80 (84%)
Foxp1	XP_038963306.1	FOXP-CC	358..425	CDD:465036	63/66 (95%)
		COG5025	493..>707	CDD:227358	193/229 (84%)
		FH_FOXP2	520..601	CDD:410839	68/86 (79%)