DRSC/TRiP Functional Genomics Resources

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Protein Alignment DAPP1 and YLR157C-B

DIOPT Version :9

Sequence 1:NP_055210.2 Gene:DAPP1 / 27071 HGNCID:16500 Length:280 Species:Homo sapiens
Sequence 2:NP_058169.1 Gene:YLR157C-B / 850853 SGDID:S000007374 Length:1755 Species:Saccharomyces cerevisiae


Alignment Length:267 Identity:52/267 - (19%)
Similarity:85/267 - (31%) Gaps:91/267 - (34%)


- Green bases have known domain annotations that are detailed below.


Human    12 STQDPSDLWSRSDGEAELLQDLGWYHGNLTRHAAEA----LLLSNGCDGSYLLR--------DSN 64
            ||.:|..|.::.|  ..|.|:|.....|.|.|:.:.    |||.:|...: |:|        .||
Yeast   420 STTEPIQLNNKHD--LHLGQELTESTVNHTNHSDDELPGHLLLDSGASRT-LIRSAHHIHSASSN 481

Human    65 ETTGLYSLSVR-----------------AKDSVKHFHVEYTGYSFKFGFNEFSSLKDFVKHFANQ 112
            ....:.....|                 .|.|:|..|.....|.. ...||.::: |....|...
Yeast   482 PDINVVDAQKRNIPINAIGDLQFHFQDNTKTSIKVLHTPNIAYDL-LSLNELAAV-DITACFTKN 544

Human   113 PLIGSETGTLMV------------LKHPYPRKVEEPSIYESVRVHTAMQTGRTEDDLV------P 159
            .|..|: ||::.            .|:..|..:..|:|.   .|||:..|.:.....:      .
Yeast   545 VLERSD-GTVLAPIVKYGDFYWVSKKYLLPSNISVPTIN---NVHTSESTRKYPYPFIHRMLAHA 605

Human   160 TAPSLGTKEGYLTKQGGLVKTWKTRWFTLHRNELKYFKDQMSPEPIRILDLTECSAVQFDYSQER 224
            .||::.                    ::|..|.:.||.:.         |:...||:.:....  
Yeast   606 NAPTIR--------------------YSLKNNTITYFNES---------DVDWSSAIDYQCPD-- 639

Human   225 VNCFCLV 231
                ||:
Yeast   640 ----CLI 642

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DAPP1NP_055210.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..20 3/7 (43%)
SH2_DAPP1_BAM32_like 28..119 CDD:198218 26/119 (22%)
PH_DAPP1 163..258 CDD:269977 9/69 (13%)
YLR157C-BNP_058169.1 TYA 17..114 CDD:279373
rve 664..782 CDD:279057
RVT_2 1281..1494 CDD:285028
RNase_HI_RT_Ty1 1606..1742 CDD:260004
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0017
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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