DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DAPP1 and osp

DIOPT Version :9

Sequence 1:	NP_055210.2	Gene:	DAPP1 / 27071	HGNCID:	16500	Length:	280	Species:	Homo sapiens
Sequence 2:	NP_001162975.1	Gene:	osp / 34850	FlyBaseID:	FBgn0003016	Length:	1566	Species:	Drosophila melanogaster

Alignment Length:	99	Identity:	26/99 - (26%)
Similarity:	46/99 - (46%)	Gaps:	8/99 - (8%)

- Green bases have known domain annotations that are detailed below.

Human   163 SLGTKEGYLTKQGGLVKTWKTRWFTLHRNELKYFKDQMSPEPIR-----ILDLTECSAVQFDYSQ 222
            ||..|:|:|.||......|...||||....|.|::|.:..|  |     :||:...::|..:.:.
  Fly   505 SLNAKKGWLMKQDNRTCEWSKHWFTLSGAALFYYRDPLCEE--RGVLDGVLDVNSLTSVIPEPAA 567

Human   223 ERVNCFCL-VFPFRTFYLCAKTGVEADEWIKILR 255
            .:.:.|.| .:..:...|.:.:....:.|:.:||
  Fly   568 SKQHAFQLTTWDKQRLVLASLSPSSRNSWLAVLR 601

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DAPP1	NP_055210.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		SH2_DAPP1_BAM32_like	28..119	CDD:198218
		PH_DAPP1	163..258	CDD:269977	26/99 (26%)
osp	NP_001162975.1	PH_RIP	48..191	CDD:269942
		PH	85..185	CDD:278594
		PH_M-RIP	509..613	CDD:270094	24/95 (25%)
		PH	509..603	CDD:278594	24/95 (25%)
		SbcC	726..1353	CDD:223496
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910