DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DAPP1 and dock

DIOPT Version :9

Sequence 1:	NP_055210.2	Gene:	DAPP1 / 27071	HGNCID:	16500	Length:	280	Species:	Homo sapiens
Sequence 2:	NP_001259845.1	Gene:	dock / 33262	FlyBaseID:	FBgn0010583	Length:	548	Species:	Drosophila melanogaster

Alignment Length:	124	Identity:	39/124 - (31%)
Similarity:	58/124 - (46%)	Gaps:	16/124 - (12%)

- Green bases have known domain annotations that are detailed below.

Human    22 RSDGEAELLQDLG------------WYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSV 74
            |::|.....|..|            ||:|.:||...:.:|..:|.||.:|:|||....|.||:|:
  Fly   423 RNEGNKPAAQSSGQPIERPNLAGKSWYYGAITRSQCDTVLNGHGHDGDFLIRDSETNMGDYSVSL 487

Human    75 RAKDSVKHF--HVEYTGYSFKFGFNEFSSLKDFVKHFANQPLIGSETGTLMVLKHPYPR 131
            :|....|||  |||...|.  .|..:|.||...|.|:...|:..::.|..:.|....|:
  Fly   488 KAPGRNKHFRVHVEQNMYC--IGQRKFHSLDQLVDHYQRAPIYTNKQGEKLYLVRSLPK 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DAPP1	NP_055210.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		SH2_DAPP1_BAM32_like	28..119	CDD:198218	34/104 (33%)
		PH_DAPP1	163..258	CDD:269977
dock	NP_001259845.1	SH3_Nck_1	154..204	CDD:212699
		SH3_Nck_2	256..308	CDD:212700
		SH3_Nck_3	328..383	CDD:212701
		SH2_Nck_family	446..538	CDD:198196	33/93 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910