DRSC/TRiP Functional Genomics Resources

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Protein Alignment DAPP1 and CG42271

DIOPT Version :9

Sequence 1:NP_055210.2 Gene:DAPP1 / 27071 HGNCID:16500 Length:280 Species:Homo sapiens
Sequence 2:NP_996434.2 Gene:CG42271 / 2768892 FlyBaseID:FBgn0259166 Length:1280 Species:Drosophila melanogaster


Alignment Length:244 Identity:46/244 - (18%)
Similarity:81/244 - (33%) Gaps:87/244 - (35%)


- Green bases have known domain annotations that are detailed below.


Human    16 PSDLWSRSDGEAELLQDLGWYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVRAKDSV 80
            |.|||.|  |:..|::...|:..|.:..:                          ||.:||.||:
  Fly   680 PPDLWPR--GQPPLMRSNSWHPSNSSPSS--------------------------SLDIRAIDSL 716

Human    81 KHFHVEYTGYSFKFGFNEFSSLKDFVKHFANQPLIGSETGTLMVLKHPYPRKVEEPSIYESVRVH 145
            :|....|.        :...||:.     ..||  |.:...          :.:|.:.|:|:.|.
  Fly   717 QHVVKCYN--------DHLRSLEQ-----GRQP--GRQADD----------EEQEEATYQSLPVA 756

Human   146 TAMQTGRTEDDLVPTAPS--------------LG---TKEGYLTKQGGLVKTWKTRWFTLHRNEL 193
            ...|:..:....:|.:.:              :|   .::.:.....|.:.| |....:...|  
  Fly   757 WQTQSEVSAGTQIPPSDNPADLSVLQLIDLDEIGRQAQRQRHHQPPAGFLDT-KLMSSSPSAN-- 818

Human   194 KYFKDQMSPEPIRILDLTECSAVQFDYSQERVNCFCLVFPFRTFYLCAK 242
             |::....|||   ||||:.:.        ..:..|||...:.|  |.:
  Fly   819 -YYRPTEEPEP---LDLTQLNI--------EASVMCLVSKLKFF--CGR 853

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DAPP1NP_055210.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..20 2/3 (67%)
SH2_DAPP1_BAM32_like 28..119 CDD:198218 16/90 (18%)
PH_DAPP1 163..258 CDD:269977 18/97 (19%)
CG42271NP_996434.2 PH_INPP4A_INPP4B 1..145 CDD:270091
PH 21..123 CDD:278594
C2 201..318 CDD:301316
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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