Protein Alignment GJB3 and Gjb3

DIOPT Version :10

• Sequence 1: NP_076872.1
• Gene: GJB3 / 2707
• HGNCID: 4285
• Length: 270
• Species: Homo sapiens
• Sequence 2: NP_032152.1
• Gene: Gjb3 / 14620
• MGIID: 95721
• Length: 270
• Species: Mus musculus
• Alignment Length: 270
• Identity: 223/270 - (82%)
• Similarity: 247/270 - (91%)
• Gaps: 0/270 - (0%)

Human     1 MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCTNVCY 65
            ||||.||.||||||:||||||||||||||||||||||||||||||||||||||||:|||||||||
Mouse     1 MDWKKLQDLLSGVNQYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTRQPGCTNVCY 65

Human    66 DNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNAGKKHGGLWWT 130
            ||:||||||||||||||||||||:||||||||||||||:||||||:||||||.:.||||||||||
Mouse    66 DNFFPISNIRLWALQLIFVTCPSMLVILHVAYREERERKHRQKHGEQCAKLYSHPGKKHGGLWWT 130

Human   131 YLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGAS 195
            ||||||||||||.:|||:||||||||.||||||||::.||||.||||||||||||:|||||||||
Mouse   131 YLFSLIFKLIIELVFLYVLHTLWHGFTMPRLVQCASIVPCPNTVDCYIARPTEKKVFTYFMVGAS 195

Human   196 AVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSASRASTCRCHHKLVEAGEVDPDPGNNKL 260
            ||||:|||||:||||.||::||:.|.|.....|...|:||||||||||||:|:|:.:.||.:.||
Mouse   196 AVCIILTICEICYLIFHRIMRGISKGKSTKSISSPKSSSRASTCRCHHKLLESGDPEADPASEKL 260

Human   261 QASAPNLTPI 270
            |||||:||||
Mouse   261 QASAPSLTPI 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GJB3	NP_076872.1	Connexin	2..211	CDD:459638	186/208 (89%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	250..270		11/19 (58%)
Gjb3	NP_032152.1	Connexin	2..211	CDD:459638	186/208 (89%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	246..270		13/23 (57%)