Protein Alignment PPA2 and Nurf-38

DIOPT Version :10

• Sequence 1: NP_789845.1
• Gene: PPA2 / 27068
• HGNCID: 28883
• Length: 334
• Species: Homo sapiens
• Sequence 2: NP_523849.3
• Gene: Nurf-38 / 37922
• FlyBaseID: FBgn0016687
• Length: 338
• Species: Drosophila melanogaster
• Alignment Length: 302
• Identity: 160/302 - (52%)
• Similarity: 207/302 - (68%)
• Gaps: 16/302 - (5%)

Human    32 MALYHTEERGQPCSQNYRLFFKNVTGHYISPFHDIPLKVNSKEENGIPMKKARNDEYENLFNMIV 96
            ||||.|.|:|...|.:|.|:|||..|:.|||.|||||..|               |.:.::||:|
  Fly    49 MALYETVEKGAKNSPSYSLYFKNKCGNVISPMHDIPLYAN---------------EEKTIYNMVV 98

Human    97 EIPRWTNAKMEIATKEPMNPIKQYVKDGKLRYVANIFPYKGYIWNYGTLPQTWEDPHEKDKSTNC 161
            |:||||||||||:.|.|||||||.:|.||||:|||.||:||||||||.||||||:|...:.||.|
  Fly    99 EVPRWTNAKMEISLKTPMNPIKQDIKKGKLRFVANCFPHKGYIWNYGALPQTWENPDHIEPSTGC 163

Human   162 FGDNDPIDVCEIGSKILSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKF 226
            .||||||||.|||.::...|:|:.||:||.:|||||||||||:|||:.|||.|||.:||.||.::
  Fly   164 KGDNDPIDVIEIGYRVAKRGDVLKVKVLGTIALIDEGETDWKIIAIDVNDPLASKVNDIADVDQY 228

Human   227 KPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCT 291
            .||.|.||:.||::||:|||||||||||||:.||..||..:|..||:.|:.|:.:....|:|:.|
  Fly   229 FPGLLRATVEWFKIYKIPDGKPENQFAFNGDAKNADFANTIIAETHKFWQNLVHQSPASGSISTT 293

Human   292 NVQISDSPFRCTQEEA-RSLVESVSSSPNKESNEEEQVWHFL 332
            |:...:|.....:||| :.|.|:......:|.::....|||:
  Fly   294 NITNRNSEHVIPKEEAEKILAEAPDGGQVEEVSDTVDTWHFI 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PPA2	NP_789845.1	pyrophosphatase	4..286	CDD:469666	146/253 (58%)
Nurf-38	NP_523849.3	pyrophosphatase	26..292	CDD:469666	148/257 (58%)