Protein Alignment ABL2 and LSB1

DIOPT Version :10

• Sequence 1: NP_009298.1
• Gene: ABL2 / 27
• HGNCID: 77
• Length: 1182
• Species: Homo sapiens
• Sequence 2: NP_011652.1
• Gene: LSB1 / 853037
• SGDID: S000003368
• Length: 241
• Species: Saccharomyces cerevisiae
• Alignment Length: 100
• Identity: 30/100 - (30%)
• Similarity: 46/100 - (46%)
• Gaps: 12/100 - (12%)

Human    94 RWSSKENLLGATESDPNLFV-ALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWV 157
            :|..  |......:|...:| |||||.|..|..||:..|:|::|| ...:.:|...:|.|..|..
Yeast    41 KWDG--NQRSPQNADTEEYVEALYDFEAQQDGDLSLKTGDKIQVL-EKISPDWYRGKSNNKIGIF 102

Human   158 PSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLIN 192
            |:||:.|.        :....|..:||...||.::
Yeast   103 PANYVKPA--------FTRSASPKSAEAASSSTVS 129

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ABL2	NP_009298.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..47
		CAP	2..106		2/11 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	60..80
		SH3_Abl	111..164	CDD:212784	21/53 (40%)
		SH2_ABL	169..262	CDD:198189	5/23 (22%)
		PTKc_Abl	281..543	CDD:270645
		Kinase activation loop. /evidence=ECO:0000250	427..451
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	611..641
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	654..674
		Nuclear localization signal. /evidence=ECO:0000255	658..660
		F-actin-binding. /evidence=ECO:0000250	694..930
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	763..794
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	807..851
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	964..1024
		F-actin-binding. /evidence=ECO:0000250	1020..1182
		FABD	1063..1182	CDD:197885
LSB1	NP_011652.1	SH3	55..108	CDD:214620	21/53 (40%)
		PRK12323	<100..>156	CDD:481241	10/37 (27%)