Protein Alignment CHORDC1 and mora

DIOPT Version :10

• Sequence 1: NP_036256.2
• Gene: CHORDC1 / 26973
• HGNCID: 14525
• Length: 332
• Species: Homo sapiens
• Sequence 2: NP_651226.1
• Gene: mora / 42874
• FlyBaseID: FBgn0029503
• Length: 354
• Species: Drosophila melanogaster
• Alignment Length: 338
• Identity: 145/338 - (42%)
• Similarity: 218/338 - (64%)
• Gaps: 26/338 - (7%)

Human     5 CYNRGCGQRFDPETNSDDACTYHPGVPVFHDALKGWSCCKRRTTDFSDFLSIVGCTKGRHNSEKP 69
            ||||||||.|||:||:|::|.:|||.|.||||.||||||.:::.||::||:|.|||..:|::.||
  Fly     4 CYNRGCGQLFDPQTNNDESCRHHPGEPFFHDAYKGWSCCNKKSVDFTEFLNIKGCTLAKHSNVKP 68

Human    70 PEPVKPEVKTTEKKELCELKPKFQEHIIQAPKPVEAIKRPSPDEPMTNLELKISASLKQALDKLK 134
            |||.||....::|.|:.|::...:          ||:.||..|.|:|.::..::.:||..:..:|
  Fly    69 PEPEKPVKDESDKDEVIEVRAPIR----------EALPRPPIDSPLTVIQPTVAPALKDMVFAVK 123

Human   135 LSSGNEENKKEEDNDEIKIGTSCKNGGCSKTYQGLESLEEVCVYHSGVPIFHEGMKYWSCCRRKT 199
            ..:.      ::.:|.|::||:|||.||:.::.|..|....|.||.||||||||||:||||:::|
  Fly   124 TPAA------QKSSDAIEVGTTCKNNGCTYSFTGNSSDFGECTYHPGVPIFHEGMKFWSCCQKRT 182

Human   200 SDFNTFLAQEGCTKGKHMWTKKDAGKKVVPCRHDWHQTGGEVTISVYAKNSLPELSRVEANSTLL 264
            |||:.|:||:|||.|:|.|.|::..||||.||:|||||...|.:::|||......|.:|.|...|
  Fly   183 SDFSQFMAQKGCTYGEHKWVKENDDKKVVQCRYDWHQTATNVVMAIYAKKYDYSQSVIELNPIRL 247

Human   265 NVHIVF--EGEKEFDQNVKLWGVIDVKRSYVTMTATKIEITMRKAEPMQWASL-----ELPAAKK 322
            :|::||  :....||.:::|.|:::|..:...|..||:||.:.|.||..|::|     :||..||
  Fly   248 HVNLVFPEQDNARFDLDLELRGIVNVSNASAHMYGTKVEIKLPKLEPGSWSNLNFPNKKLPVVKK 312

Human   323 ---QEKQKDATTD 332
               :||:|...:|
  Fly   313 SQVEEKKKQEESD 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CHORDC1	NP_036256.2	Interaction with PPP5C. /evidence=ECO:0000250	2..77		45/71 (63%)
		CHORD	3..64	CDD:461502	37/58 (64%)
		Interaction with HSP90AA1 and HSP90AB1. /evidence=ECO:0000250	65..316		99/257 (39%)
		CHORD	155..216	CDD:461502	36/60 (60%)
		p23_melusin_like	230..316	CDD:107238	33/92 (36%)
mora	NP_651226.1	CHORD	3..63	CDD:461502	37/58 (64%)
		CHORD	138..199	CDD:461502	36/60 (60%)
		p23_melusin_like	213..301	CDD:107238	32/87 (37%)