Protein Alignment GHSR and Ghsr

DIOPT Version :10

• Sequence 1: NP_940799.1
• Gene: GHSR / 2693
• HGNCID: 4267
• Length: 366
• Species: Homo sapiens
• Sequence 2: XP_017175002.1
• Gene: Ghsr / 208188
• MGIID: 2441906
• Length: 427
• Species: Mus musculus
• Alignment Length: 366
• Identity: 349/366 - (95%)
• Similarity: 355/366 - (96%)
• Gaps: 2/366 - (0%)

Human     1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTM 65
            ||||||||||..|:|| |||||||||||||.||||.||||||||||||||||||||||:||||||
Mouse    64 MWNATPSEEPEPNVTL-DLDWDASPGNDSLSDELLPLFPAPLLAGVTATCVALFVVGISGNLLTM 127

Human    66 LVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYAT 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   128 LVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYAT 192

Human   131 VLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDT 195
            ||||||||||||||||||||||||||||||||||.|||||||||||||||||||||||||||.||
Mouse   193 VLTITALSVERYFAICFPLRAKVVVTKGRVKLVILVIWAVAFCSAGPIFVLVGVEHENGTDPRDT 257

Human   196 NECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQ 260
            ||||.||||||||||||||||||:||||||||||||||||||||| ||||||.||:|||||||||
Mouse   258 NECRATEFAVRSGLLTVMVWVSSVFFFLPVFCLTVLYSLIGRKLW-RRRGDAAVGSSLRDQNHKQ 321

Human   261 TVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNI 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   322 TVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNI 386

Human   326 MSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT 366
            ||||||||||:|||||.||||||||||||||||||:|||||
Mouse   387 MSKKYRVAVFKLLGFESFSQRKLSTLKDESSRAWTKSSINT 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GHSR	NP_940799.1	7tmA_GHSR	44..334	CDD:320259	281/289 (97%)
		TM helix 1	44..71	CDD:320259	25/26 (96%)
		TM helix 2	78..103	CDD:320259	24/24 (100%)
		TM helix 3	116..146	CDD:320259	29/29 (100%)
		TM helix 4	158..180	CDD:320259	20/21 (95%)
		TM helix 5	209..238	CDD:320259	27/28 (96%)
		TM helix 6	256..286	CDD:320259	29/29 (100%)
		TM helix 7	302..327	CDD:320259	24/24 (100%)
Ghsr	XP_017175002.1	7tmA_GHSR	107..395	CDD:320259	280/288 (97%)
		TM helix 1	107..133	CDD:320259	24/25 (96%)
		TM helix 2	140..165	CDD:320259	24/24 (100%)
		TM helix 3	178..208	CDD:320259	29/29 (100%)
		TM helix 4	220..242	CDD:320259	20/21 (95%)
		TM helix 5	271..300	CDD:320259	27/28 (96%)
		TM helix 6	317..347	CDD:320259	29/29 (100%)
		TM helix 7	363..388	CDD:320259	24/24 (100%)