Protein Alignment GHSR and ghsr

DIOPT Version :10

• Sequence 1: NP_940799.1
• Gene: GHSR / 2693
• HGNCID: 4267
• Length: 366
• Species: Homo sapiens
• Sequence 2: XP_002931618.1
• Gene: ghsr / 100497774
• XenbaseID: XB-GENE-484475
• Length: 359
• Species: Xenopus tropicalis
• Alignment Length: 348
• Identity: 260/348 - (74%)
• Similarity: 302/348 - (86%)
• Gaps: 0/348 - (0%)

Human    19 LDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLS 83
            :|:..|..|.|..::.:.|||.|:|.|:|.||:.||::||:||::||||||:::::|||||||||
 Frog    12 MDYYYSSNNYSWPEDPVFLFPVPVLTGITVTCILLFIIGISGNVMTMLVVSKYKDMRTTTNLYLS 76

Human    84 SMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFP 148
            |||||||||||||||||.|||||||||||..||||||||||.|||:|:|.|||||||||||||||
 Frog    77 SMAFSDLLIFLCMPLDLYRLWQYRPWNFGSSLCKLFQFVSECCTYSTILNITALSVERYFAICFP 141

Human   149 LRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVM 213
            |:||||:|||||||||.|:|||:|.|||||||||||||||||:|.|||||:.||:|::|||||:|
 Frog   142 LKAKVVITKGRVKLVISVLWAVSFVSAGPIFVLVGVEHENGTNPLDTNECKATEYAIKSGLLTIM 206

Human   214 VWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLP 278
            ||.||||||||||||||||:|||||||||:|.......|:||:::||||||||||||||||||||
 Frog   207 VWTSSIFFFLPVFCLTVLYTLIGRKLWRRKRETIGPHTSIRDKHNKQTVKMLAVVVFAFILCWLP 271

Human   279 FHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPF 343
            |||.|||||||||.||||||.||||||||||||||||||||||||||||||||||..||...:..
 Frog   272 FHVARYLFSKSFEAGSLEIALISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAACRLFRLKQV 336

Human   344 SQRKLSTLKDESSRAWTESSINT 366
            |::...|..||||.|||||:::|
 Frog   337 SRKATYTTNDESSPAWTESNMST 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GHSR	NP_940799.1	7tmA_GHSR	44..334	CDD:320259	236/289 (82%)
		TM helix 1	44..71	CDD:320259	16/26 (62%)
		TM helix 2	78..103	CDD:320259	23/24 (96%)
		TM helix 3	116..146	CDD:320259	25/29 (86%)
		TM helix 4	158..180	CDD:320259	17/21 (81%)
		TM helix 5	209..238	CDD:320259	25/28 (89%)
		TM helix 6	256..286	CDD:320259	25/29 (86%)
		TM helix 7	302..327	CDD:320259	24/24 (100%)
ghsr	XP_002931618.1	7tmA_GHSR	37..327	CDD:320259	236/289 (82%)
		TM helix 1	37..64	CDD:320259	16/26 (62%)
		TM helix 2	71..96	CDD:320259	23/24 (96%)
		TM helix 3	109..139	CDD:320259	25/29 (86%)
		TM helix 4	151..173	CDD:320259	17/21 (81%)
		TM helix 5	202..231	CDD:320259	25/28 (89%)
		TM helix 6	249..279	CDD:320259	25/29 (86%)
		TM helix 7	295..320	CDD:320259	24/24 (100%)