Protein Alignment GHSR and ghsrb

DIOPT Version :10

• Sequence 1: NP_940799.1
• Gene: GHSR / 2693
• HGNCID: 4267
• Length: 366
• Species: Homo sapiens
• Sequence 2: XP_002666717.1
• Gene: ghsrb / 100332193
• ZFINID: ZDB-GENE-090327-1
• Length: 365
• Species: Danio rerio
• Alignment Length: 342
• Identity: 242/342 - (70%)
• Similarity: 284/342 - (83%)
• Gaps: 3/342 - (0%)

Human    27 NDSLGDEL-LQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDL 90
            |.:..||. :.|||.|:|.|:|.||..||:|||||||||:|||::::::||||||||.|||.|||
Zfish    25 NATSEDEYPVHLFPVPILTGITVTCSFLFLVGIAGNLLTILVVTKYKDMRTTTNLYLCSMALSDL 89

Human    91 LIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVV 155
            ||||||||||.|:|:||||||||.||||||||||||||:|:|.||||||||||||||||||||:|
Zfish    90 LIFLCMPLDLYRVWRYRPWNFGDELCKLFQFVSESCTYSTILNITALSVERYFAICFPLRAKVIV 154

Human   156 TKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIF 220
            |:||||.||.::|.||.|||||||:||||||||||:.|:||||:.||:|:||||||:||||||:|
Zfish   155 TRGRVKGVILLLWTVALCSAGPIFILVGVEHENGTNAWETNECKATEYAIRSGLLTMMVWVSSVF 219

Human   221 FFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYL 285
            |||||.|||||||||||:||||:. :.|...|.||:::|||||||||||.||:||||||||||||
Zfish   220 FFLPVLCLTVLYSLIGRRLWRRKE-NPVGPISSRDKSNKQTVKMLAVVVLAFVLCWLPFHVGRYL 283

Human   286 FSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKL-S 349
            .|||.|..|..|:|||:|||||||||||||||||||||||||||:|.|..:|...:....|.| |
Zfish   284 VSKSSEANSPVISQISEYCNLVSFVLFYLSAAINPILYNIMSKKFRSAACKLFRVKRAPGRSLQS 348

Human   350 TLKDESSRAWTESSINT 366
            .:..||...|.|.|.:|
Zfish   349 IVNAESVSVWNEYSWST 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GHSR	NP_940799.1	7tmA_GHSR	44..334	CDD:320259	223/289 (77%)
		TM helix 1	44..71	CDD:320259	18/26 (69%)
		TM helix 2	78..103	CDD:320259	21/24 (88%)
		TM helix 3	116..146	CDD:320259	26/29 (90%)
		TM helix 4	158..180	CDD:320259	15/21 (71%)
		TM helix 5	209..238	CDD:320259	25/28 (89%)
		TM helix 6	256..286	CDD:320259	24/29 (83%)
		TM helix 7	302..327	CDD:320259	23/24 (96%)
ghsrb	XP_002666717.1	7tm_GPCRs	43..332	CDD:475119	223/289 (77%)
		TM helix 1	45..69	CDD:410628	17/23 (74%)
		TM helix 2	78..99	CDD:410628	18/20 (90%)
		TM helix 3	116..138	CDD:410628	18/21 (86%)
		TM helix 4	161..177	CDD:410628	9/15 (60%)
		TM helix 5	209..232	CDD:410628	19/22 (86%)
		TM helix 6	260..282	CDD:410628	19/21 (90%)
		TM helix 7	300..325	CDD:410628	23/24 (96%)