Protein Alignment AMHR2 and bmpr2a

DIOPT Version :9

• Sequence 1: XP_011536475.1
• Gene: AMHR2 / 269
• HGNCID: 465
• Length: 593
• Species: Homo sapiens
• Sequence 2: XP_005165892.1
• Gene: bmpr2a / 562822
• ZFINID: ZDB-GENE-070618-1
• Length: 1013
• Species: Danio rerio
• Alignment Length: 574
• Identity: 194/574 - (33%)
• Similarity: 276/574 - (48%)
• Gaps: 101/574 - (17%)

Human     2 LGSLGLWALLPTAVEAPPNRRTCVFFEAP-------GVRGSTKTLGELLDTGTELPRAIRCLYSR 59
            :|.:.:..||.....|...:|.|.:.|.|       |.||......|        ...|||....
Zfish    12 VGLIAMVVLLGPVAAAQSEQRECAYAEQPQGLAERIGGRGEGLVFHE--------NSTIRCYQGH 68

Human    60 CCFGIWNLTQDRAQVEMQGC--RDSDEPGCESLHCDPSPRAHPSPGSTLFTCSCGTDFCNANYSH 122
            .|||:|....:...:..|||  ...|...|.......:|.:....|:..| |.|..|.||.|::.
Zfish    69 RCFGLWGKKNNGVVLVKQGCWTNVGDHQECYDRCVVTNPPSVAQNGTYRF-CCCNKDMCNLNFTE 132

Human   123 LPPPGSPGTPGSQGPQAAPGES----------IWMALVLLGLFLLLLLLLGSIILALLQRKNYRV 177
            ..||.||.|       |.|.:|          :.:|.|.:...|::||..|..:|        |.
Zfish   133 DFPPPSPTT-------AQPLQSRRLHREEVIVVALATVSMVAVLVILLFFGYRML--------RG 182

Human   178 RG----------EPVPEPRPDSGRDWSVELQELPELCFSQQVIREGGHAVVWAGQLQGKLVAIKA 232
            ||          |....|.       |::|..|.    .|::|..|.:..|:...|..:.||:|.
Zfish   183 RGKHSLHTLNILETALSPP-------SLDLDNLT----LQELIGRGRYGTVYRASLDDRSVAVKV 236

Human   233 FPPRSVAQFQAERALYELPGLQHDHIVRFITASR--GGPGRLLSGPLLVLELHPKDCVCLCPRGR 295
            |...:..||..||.:|.|. |.|::|.||:.:..  |..||  :..||:||.:|.
Zfish   237 FISANRQQFTNERMIYRLL-LDHENIARFLESEERVGTEGR--TEFLLLLEFYPH---------- 288

Human   296 APHNSLCPIGSLCHYLTQYTSDWGSSLRMALSLAQGLAFLHEERWQNGQYKPGIAHRDLSSQNVL 360
                     ||||.||:..|.||.|..|:|||:.:|||:||.|..:...|||.::||||:|:|||
Zfish   289 ---------GSLCTYLSGRTVDWLSCCRLALSVTRGLAYLHTEIQRGDVYKPAVSHRDLNSRNVL 344

Human   361 IREDGSCAIGDLGLALVLPGLTQPPAWTPTQPQGPAAIMEAGTQRYMAPELLDKTLDLQDWGMAL 425
            ::.||||.|.|.||:::|.| .:||.   ...:..:||.|.||.||||||:|:..::|:|...||
Zfish   345 VKTDGSCVISDFGLSMILTG-KRPPG---HGEEDNSAISEVGTVRYMAPEVLEGAVNLRDCESAL 405

Human   426 RRADIYSLALLLWEILSRCPDLRPDSSPPPFQLAYEAELGNTPTSDELWALAVQERRRPYIPSTW 490
            ::.|:|:|.|:.||...||.||.|..:.|.||||::||:||.||.:::.||..:|:.||..|..|
Zfish   406 KQVDVYALGLVYWETFMRCADLFPGETVPAFQLAFQAEVGNHPTIEDMQALVSREKERPKFPEAW 470

Human   491 RCFATDPDGLRELLEDCWDADPEARLTAECVQQRLAAL---------AHPQESH 535
            :..:.....|:|.:|||||.|.||||||:|.::|||.|         |.|..:|
Zfish   471 KENSLTVHSLKETMEDCWDQDAEARLTAQCAEERLAELLLIWDREKSASPALNH 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMHR2	XP_011536475.1	Pkinase	208..531	CDD:278497	135/333 (41%)
		PKc_like	208..528	CDD:304357	133/321 (41%)
bmpr2a	XP_005165892.1	Activin_recp	64..134	CDD:279413	19/70 (27%)
		S_TKc	209..499	CDD:214567	129/319 (40%)
		STKc_BMPR2_AMHR2	212..508	CDD:270956	133/321 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG3653
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D191771at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820