Protein Alignment AMHR2 and tgfbr2l

DIOPT Version :9

• Sequence 1: XP_011536475.1
• Gene: AMHR2 / 269
• HGNCID: 465
• Length: 593
• Species: Homo sapiens
• Sequence 2: XP_688938.2
• Gene: tgfbr2l / 560446
• ZFINID: ZDB-GENE-081105-143
• Length: 590
• Species: Danio rerio
• Alignment Length: 592
• Identity: 167/592 - (28%)
• Similarity: 251/592 - (42%)
• Gaps: 133/592 - (22%)

Human    56 LYSRCCFGIWNLTQDRAQVEMQG-CRDSDE-------PGCESLHCDPSPRAHPSPGSTLFTCSC- 111
            |....|..||.  :|...|.::. |.|...       ....|..|..||  |||....||.|||
Zfish    57 LAEEVCVAIWK--KDNVSVSVRTLCYDPQHMLENIMLANYSSKECLMSP--HPSEDGLLFICSCV 117

Human   112 GTDFCNANYSHLPPPGSPGTPGSQGPQAAPGESIWMALVLLGLFLLLLLLLGSIILALLQRKNYR 176
            |...||...  :...|..|....:.....|       :|::.|...||:    .::|.:....||
Zfish   118 GDQECNDRL--IFDKGPNGFSKLKSKDVIP-------VVVISLVPPLLV----AVIATMAFYLYR 169

Human   177 VRGEPVPEPR-------------PDSGR----DWSVEL--------QELPELCFS---------- 206
            .| :|..:|:             |..|:    |:|.:.        .|:...|.:
Zfish   170 TR-QPGKKPKEWGPRRTHYQSLDPAEGQANGIDFSAKRPSLSDDINSEMSSTCANNLNHNTEQLP 233

Human   207 ---QQVIREGGHAVVWAGQL------QGKLVAIKAFPPRSVAQFQAERALYELPGLQHDHIVRFI 262
               :.::.:|..|.||..:|      |.:.||:|.||....:.:..|||::....|:|:::|:|:
Zfish   234 IQLEALVGKGRFAEVWRARLSHNESGQYETVAVKIFPAVEYSSWCNERAIFSDANLKHENVVQFL 298

Human   263 TA-SRGGPGRLLSGPLLVLELHPKDCVCLCPRGRAPHNSLCPIGSLCHYLTQYTSDWGSSLRMAL 326
            || .|||..........::              .|.:|    :|:|..:|......|.....:|.
Zfish   299 TAEERGGTSATSQRQYWLI--------------MAYYN----MGNLQDFLVGNILTWAELCSLAG 345

Human   327 SLAQGLAFLHEERWQNGQYKPGIAHRDLSSQNVLIREDGSCAIGDLGLALVLP-GLTQPPAWTPT 390
            |:|:|||.||.:....|..|..||||||.|.|::::....|.:.|.||||.|. .||....
Zfish   346 SVARGLAHLHSDTTPCGIQKVPIAHRDLKSSNIVLKNQSECVLCDFGLALRLDLSLTVDDF---- 406

Human   391 QPQGPAAIMEAGTQRYMAPELLDKTLDLQDWGMALRRADIYSLALLLWEILSRCPDL-RPDSSPP 454
                 |...:.||.||||||:|:..::|:|. .:.::.||||:||::||::|||..: ...|..|
Zfish   407 -----ANSGQVGTARYMAPEVLESRVNLEDL-ESFKQIDIYSMALVMWEMVSRCDVIGEVKSYEP 465

Human   455 PFQLAYEAELGNTPTSDELWALAVQERRRPYIPSTWRCFATDPDGLREL---LEDCWDADPEARL 516
            ||    .:::...|..|.:..|.:::|.||.||.:|    |...|::.|   :.:|||.||||||
Zfish   466 PF----GSKVCEQPCVDSMRDLVLRDRGRPDIPDSW----TTHSGMQLLCATITECWDHDPEARL 522

Human   517 TAECVQQRLAALAHPQESHPFPESCPRGCPPLCPEDCTSIPAPTILPCRPQRSACHFSVQQGPCS 581
            ||.||.:|...||..:..:......| ..||  .||.|    || ||..|            ||:
Zfish   523 TAHCVVERFNTLAQEELENSICTHTP-STPP--TEDQT----PT-LPSHP------------PCT 567

Human   582 RNPQPAC 588
            .:....|
Zfish   568 DHSADIC 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMHR2	XP_011536475.1	Pkinase	208..531	CDD:278497	111/334 (33%)
		PKc_like	208..528	CDD:304357	109/331 (33%)
tgfbr2l	XP_688938.2	ecTbetaR2	28..131	CDD:286061	23/79 (29%)
		S_TKc	235..525	CDD:214567	105/325 (32%)
		STKc_TGFbR2_like	238..535	CDD:270957	109/332 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG3653
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810