Protein Alignment AMHR2 and acvr2aa

DIOPT Version :9

• Sequence 1: XP_011536475.1
• Gene: AMHR2 / 269
• HGNCID: 465
• Length: 593
• Species: Homo sapiens
• Sequence 2: XP_021334336.1
• Gene: acvr2aa / 553359
• ZFINID: ZDB-GENE-980526-227
• Length: 538
• Species: Danio rerio
• Alignment Length: 532
• Identity: 142/532 - (26%)
• Similarity: 225/532 - (42%)
• Gaps: 128/532 - (24%)

Human    61 CFGIWNLTQDRAQVEMQGCRDSDEPGCESLHC-----DPSPRAHPSPGSTLFTCSCGTDFCNANY 120
            ||..|.......::..|||...|....:|..|     ||.          :|.|.|..:.||..:
Zfish    61 CFATWRNVSGTVEIVKQGCWLDDVNCYDSTECVEKKEDPD----------VFFCCCEGNMCNEKF 115

Human   121 SHLPPPGSPGTPGSQGPQAAPGES------------IWMAL------------VLLGLFLLLLLL 161
            .:             .|..||.:|            ::.|.            .||...:.::.:
Zfish   116 FY-------------NPNTAPVQSKAPFSDTKSDTKVFKATSNPLTQKPPLFSTLLYSIVPIMGI 167

Human   162 LGSIILALLQRKNYRVRGEPV--------------PEPRPDSGRDWSVELQELPELCFSQQVIRE 212
            ...::|:....:::::...||              |.|.|.|.......||.|       ::...
Zfish   168 AAIVLLSFWMYRHHKLAYPPVLVPTQHAFHIMIEDPGPMPPSPTLVQKPLQLL-------EIKAR 225

Human   213 GGHAVVWAGQLQGKLVAIKAFPPRSVAQFQAERALYELPGLQHDHIVRFITASRGGPGRLLSGPL 277
            |....||..||....||:|.||.:....:|.|..:|.:||::|::|::||.|.:.|..  |...|
Zfish   226 GRFGCVWKAQLLNDYVAVKIFPIQDKLSWQNEYDIYNIPGMRHENILQFIGAEKRGSN--LDIEL 288

Human   278 -LVLELHPKDCVCLCPRGRAPHNSLCPIGSLCHYLTQYTSDWGSSLRMALSLAQGLAFLHEE--R 339
             |:...|.|                   .||..||......|.....:|.::|:|||:||.:  .
Zfish   289 WLITAYHEK-------------------SSLTDYLKANVVTWNELCHIAQTMARGLAYLHSDFPG 334

Human   340 WQNGQYKPGIAHRDLSSQNVLIREDGSCAIGDLGLALVLPGLTQPPAWTPTQPQGPAA---IMEA 401
            .::| :||.|||||..|:|||::.:.:..|.|.||||....             |.:|   ..:.
Zfish   335 HRDG-HKPAIAHRDFKSKNVLLKTNLTACIADFGLALKFEA-------------GKSAGDTHGQV 385

Human   402 GTQRYMAPELLDKTLDLQ-DWGMALRRADIYSLALLLWEILSRCPDLRPDSSPPPFQLAYEAELG 465
            ||:||||||:|:..::.| |   |..|.|:|::.|:|||:.:||  ...|.....:.|.:|.|:|
Zfish   386 GTRRYMAPEVLEGAINFQRD---AFLRIDMYAVGLVLWELAARC--TASDGPVDEYMLPFEEEVG 445

Human   466 NTPTSDELWALAVQERRRPYIPSTWRCFATDPDGLR---ELLEDCWDADPEARLTAECVQQRLAA 527
            ..||.:::..:.|.::.||.:...|:    ...||.   |.:|:|||.:.||||:|.||::|:..
Zfish   446 QHPTLEDMQEVVVHKKLRPTLRECWQ----KHPGLAMLCETIEECWDHEAEARLSAGCVEERVVQ 506

Human   528 LAHPQESHPFPE 539
            :.. |.|...||
Zfish   507 MQR-QTSVSAPE 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMHR2	XP_011536475.1	Pkinase	208..531	CDD:278497	105/332 (32%)
		PKc_like	208..528	CDD:304357	105/329 (32%)
acvr2aa	XP_021334336.1	Activin_recp	43..115	CDD:307282	16/63 (25%)
		STKc_ACVR2a	221..510	CDD:271043	105/333 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG3653
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D191771at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820