Protein Alignment GFI1 and CG7691

DIOPT Version :10

• Sequence 1: NP_005254.2
• Gene: GFI1 / 2672
• HGNCID: 4237
• Length: 422
• Species: Homo sapiens
• Sequence 2: NP_650728.1
• Gene: CG7691 / 42228
• FlyBaseID: FBgn0038626
• Length: 283
• Species: Drosophila melanogaster
• Alignment Length: 106
• Identity: 37/106 - (34%)
• Similarity: 47/106 - (44%)
• Gaps: 6/106 - (5%)

Human   247 RLLLGGGSYKCIKCSKVFSTPHGLEVHVRRSHSGTRPFACE--MCGKTFGHAVSLEQH-KAVHSQ 308
            ||...||.::||.|.|.|.....|..|. |:|:|.:||.|.  .|.|.|....:|..| :.:...
  Fly   181 RLKRVGGQFECIDCDKKFDHSWMLTAHT-RTHTGEKPFVCPDGSCRKAFSDRSNLRSHQRTMGHH 244

Human   309 ERSFDCKICGKSFKRSSTLSTHLLIHSDTRPYPCQYCGKRF 349
            |....|..|||.|.:.|.|:.|.|  ...|.|......|||
  Fly   245 EWQHQCGQCGKYFSQFSYLNRHSL--DACRKYLLSVMHKRF 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GFI1	NP_005254.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..109
		SNAG domain. /evidence=ECO:0000250	1..20
		Required for interaction with RELA. /evidence=ECO:0000269|PubMed:20547752	140..257		4/9 (44%)
		COG5048	<254..416	CDD:227381	33/99 (33%)
		C2H2 Zn finger	257..278	CDD:275368	8/20 (40%)
		C2H2 Zn finger	286..306	CDD:275368	6/22 (27%)
		C2H2 Zn finger	314..334	CDD:275368	9/19 (47%)
		C2H2 Zn finger	342..362	CDD:275368	3/8 (38%)
		C2H2 Zn finger	370..390	CDD:275368
		C2H2 Zn finger	398..417	CDD:275368
CG7691	NP_650728.1	COG5048	188..>271	CDD:227381	28/85 (33%)
		C2H2 Zn finger	191..211	CDD:275368	8/20 (40%)
		C2H2 Zn finger	219..244	CDD:275368	6/24 (25%)
		C2H2 Zn finger	250..266	CDD:275368	7/15 (47%)