Protein Alignment GFI1 and rst2

DIOPT Version :10

• Sequence 1: NP_005254.2
• Gene: GFI1 / 2672
• HGNCID: 4237
• Length: 422
• Species: Homo sapiens
• Sequence 2: NP_593288.1
• Gene: rst2 / 2543031
• PomBaseID: SPAC6F12.02
• Length: 567
• Species: Schizosaccharomyces pombe
• Alignment Length: 103
• Identity: 28/103 - (27%)
• Similarity: 45/103 - (43%)
• Gaps: 15/103 - (14%)

Human   324 SSTLSTHLLIHSDTRPYPCQYCGKRFHQKSDMKKHTFIHTGEKPHKCQVCGKAFSQSSNLITHSR 388
            :|..:|...:.|:::|.......|:.......|        .|.:.|:.|.:||::..:|..|.|
pombe    34 TSNANTPSSVTSNSKPVASSTAAKKDPNAPPQK--------VKQYVCETCTRAFARLEHLKRHIR 90

Human   389 KHTGFKPFGCDL-------CGKGFQRKVDLRRHRETQH 419
            .||..|||.|..       ||:.|.|:..|.||::..|
pombe    91 SHTNEKPFTCSEIDGLPTGCGRQFSRRDLLLRHQQKIH 128

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GFI1	NP_005254.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..109
		SNAG domain. /evidence=ECO:0000250	1..20
		Required for interaction with RELA. /evidence=ECO:0000269|PubMed:20547752	140..257
		COG5048	<254..416	CDD:227381	27/98 (28%)
		C2H2 Zn finger	257..278	CDD:275368
		C2H2 Zn finger	286..306	CDD:275368
		C2H2 Zn finger	314..334	CDD:275368	2/9 (22%)
		C2H2 Zn finger	342..362	CDD:275368	2/19 (11%)
		C2H2 Zn finger	370..390	CDD:275368	7/19 (37%)
		C2H2 Zn finger	398..417	CDD:275368	8/25 (32%)
rst2	NP_593288.1	COG5048	37..547	CDD:227381	27/100 (27%)
		C2H2 Zn finger	72..92	CDD:275368	7/19 (37%)
		C2H2 Zn finger	100..128	CDD:275368	8/27 (30%)