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Protein Alignment GFAP and BIK1

DIOPT Version :10

Sequence 1:	NP_001350775.1	Gene:	GFAP / 2670	HGNCID:	4235	Length:	472	Species:	Homo sapiens
Sequence 2:	NP_009901.1	Gene:	BIK1 / 850328	SGDID:	S000000534	Length:	440	Species:	Saccharomyces cerevisiae

Alignment Length:	354	Identity:	72/354 - (20%)
Similarity:	130/354 - (36%)	Gaps:	98/354 - (27%)

- Green bases have known domain annotations that are detailed below.

Human    79 RFASYIEKVRFLE------------QQNKALAAELNQLR----AKEPTKLADVYQAELRELRLRL 127
            :.||.|||....:            .:|:::....||..    .|.||.             :|.
Yeast    72 KVASLIEKASISQTSRRTTMEPLSIPKNRSIVRLTNQFSPMDDPKSPTP-------------MRS 123

Human   128 DQLTANSARLEVERDNLAQDLATVRQKLQDETNLRLEAENNLAAYRQEADEATLARLDLERKIES 192
            .::|:..:..:...|..|.|....::...|....|:|.::.|::.|:.....|          ..
Yeast   124 FRITSRHSGNQQSMDQEASDHHQQQEFGYDNREDRMEVDSILSSDRKANHNTT----------SD 178

Human   193 LEEEIRFLRKIHEEEV----RELQ---EQLARQQVHVE--LDVAKPDLTAALKEIRTQYEAMASS 248
            .:.:...:..::..||    ||.|   |:|.|:|:|.:  ||    |....|:|::..::
Yeast   179 WKPDNGHMNDLNSSEVTIELREAQLTIEKLQRKQLHYKRLLD----DQRMVLEEVQPTFD----- 234

Human   249 NMHEAEEWYRSKFADLTDAAARNAELLRQAKHEANDYRRQLQSLTCDLESLRGTNESLERQMREQ 313
             .:||....|.|..|         .|.:|.:.|.....:|.|....:.|.|......|..:::|.
Yeast   235 -RYEATIQEREKEID---------HLKQQLELERRQQAKQKQFFDAENEQLLAVVSQLHEEIKEN 289

Human   314 EERHVRE-----AASYQEALARLEEEGQSLKDEMARH------------------LQEYQDLLNV 355
            |||::..     |....|.|.:..|:.::::|:...|                  .:|||: |:.
Yeast   290 EERNLSHNQPTGANEDVELLKKQLEQLRNIEDQFELHKTKWAKEREQLKMHNDSLSKEYQN-LSK 353

Human   356 KLAL-------DIEIATYRKLLEGEENRI 377
            :|.|       ..|:|:..|.||....:|
Yeast   354 ELFLTKPQDSSSEEVASLTKKLEEANEKI 382

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.