Protein Alignment AMFR and Amfr

DIOPT Version :9

• Sequence 1: NP_001310441.1
• Gene: AMFR / 267
• HGNCID: 463
• Length: 675
• Species: Homo sapiens
• Sequence 2: XP_038954087.1
• Gene: Amfr / 361367
• RGDID: 1311551
• Length: 643
• Species: Rattus norvegicus
• Alignment Length: 675
• Identity: 603/675 - (89%)
• Similarity: 617/675 - (91%)
• Gaps: 32/675 - (4%)

Human     1 MPLLFLERFPWPSLRTYTGLSGLALLGTIISAYRALSQPEAGPGEPDQLTASLQPEPPAPARPSA 65
            |||||||||||||||||||||||||||||:||||||||||.|.|||:.|||.||||..||||.:.
  Rat     1 MPLLFLERFPWPSLRTYTGLSGLALLGTIVSAYRALSQPEDGSGEPEPLTAPLQPEALAPARLTP 65

Human    66 GGPRARDVAQYLLSDSLFVWVLVNTACCVLMLVAKLIQCIVFGPLRVSERQHLKDKFWNFIFYKF 130
            ||||.||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat    66 GGPRVRDVAQYLLSDSLFVWVLVNTACCVLMLVAKLIQCIVFGPLRVSERQHLKDKFWNFIFYKF 130

Human   131 IFIFGVLNVQTVEEVVMWCLWFAGLVFLHLMVQLCKDRFEYLSFSPTTPMSSHGRVLSLLVAMLL 195
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||:||||
  Rat   131 IFIFGVLNVQTVEEVVMWCLWFAGLVFLHLMVQLCKDRFEYLSFSPTTPMSSHGRVLSLLIAMLL 195

Human   196 SCCGLAAVCSITGYTHGMHTLAFMAAESLLVTVRTAHVILRYVIHLWDLNHEGTWEGKGTYVYYT 260
            ||||||.||.:||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   196 SCCGLAVVCCVTGYTHGMHTLAFMAAESLLVTVRTAHVILRYVIHLWDLNHEGTWEGKGTYVYYT 260

Human   261 DFVMELTLLSLDLMHHIHMLLFGNIWLSMASLVIFMQLRYLFHEVQRRIRRHKNYLRVVGNMEAR 325
            ||||||.||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   261 DFVMELMLLSLDLMHHIHMLLFGNIWLSMASLVIFMQLRYLFHEVQRRIRRHKNYLRVVGNMEAR 325

Human   326 FAVATPEELAVNNDDCAICWDSMQAARKLPCGHLFHNSCLRSWLEQDTSCPTCRMSLNIADNNRV 390
            |||||.|||||||||||||||||||||||||||||||||||||||||||||||||||||||.:|.
  Rat   326 FAVATAEELAVNNDDCAICWDSMQAARKLPCGHLFHNSCLRSWLEQDTSCPTCRMSLNIADGSRA 390

Human   391 REEHQGENLDENLVPVAAAEGRPRLNQHNHFFHFDGDDSSMRVTAPEDVPVGQEVEVVDSDTDAP 455
            ||:|||||||||||||||||||||||||||||||||
  Rat   391 REDHQGENLDENLVPVAAAEGRPRLNQHNHFFHFDG----------------------------- 426

Human   456 DLWSRIASWLPSFSVEVMHTTNILGITQASNSQLNAMAHQIQEMFPQVPYHLVLQDLQLTRSVEI 520
               |||||||||||||||||||||||||||||||||||||||||||||||||||||||:||||||
  Rat   427 ---SRIASWLPSFSVEVMHTTNILGITQASNSQLNAMAHQIQEMFPQVPYHLVLQDLQMTRSVEI 488

Human   521 TTDNILEGRIQVPFPTQRSDSIRPALNSPVERPSSDQEEGETSAQTERVPLDLSPRLEETLDFGE 585
            |||||||||||||||.|||||:|||||||||||.:|.||||.|.|||||||||||||||||||.|
  Rat   489 TTDNILEGRIQVPFPVQRSDSLRPALNSPVERPGTDLEEGEASVQTERVPLDLSPRLEETLDFSE 553

Human   586 VEVEPSEVEDFEARGSRFSKSADERQRMLVQRKDELLQQARKRFLNKSSEDDAASESFLPSEGAS 650
            ||:||.||||||||||||||||||||||||||||:|||||||||||||||||.|||..|||||.|
  Rat   554 VELEPVEVEDFEARGSRFSKSADERQRMLVQRKDDLLQQARKRFLNKSSEDDGASERLLPSEGTS 618

Human   651 SDPVTLRRRMLAAAAERRLQKQQTS 675
            ||||||||||||||||||||:|||:
  Rat   619 SDPVTLRRRMLAAAAERRLQRQQTT 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMFR	NP_001310441.1	None
Amfr	XP_038954087.1	HRD1	86..>382	CDD:227568	289/295 (98%)
		RING-H2_AMFR	339..382	CDD:319369	42/42 (100%)
		CUE_AMFR	458..498	CDD:270604	38/39 (97%)
		G2BR	575..600	CDD:375868	23/24 (96%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83696252
Domainoid	1	1.000	606	1.000	Domainoid score	I4753
eggNOG	0	0.000	Not matched by this tool.
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H888
Inparanoid	1	1.050	1176	1.000	Inparanoid score	I4231
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG55068
OrthoDB	1	1.010	-	-		D105040at32523
OrthoFinder	1	1.000	-	-		FOG0006872
OrthoInspector	1	1.000	-	-		oto136614
orthoMCL	1	0.900	-	-		OOG6_105132
Panther	1	1.100	-	-	LDO	PTHR15067
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3836
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	16.410