Protein Alignment GDI1 and Gdi

DIOPT Version :10

• Sequence 1: NP_001484.1
• Gene: GDI1 / 2664
• HGNCID: 4226
• Length: 447
• Species: Homo sapiens
• Sequence 2: NP_523524.2
• Gene: Gdi / 34264
• FlyBaseID: FBgn0004868
• Length: 443
• Species: Drosophila melanogaster
• Alignment Length: 448
• Identity: 301/448 - (67%)
• Similarity: 368/448 - (82%)
• Gaps: 6/448 - (1%)

Human     1 MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLEGPPES 65
            |:||||.|||||||.||||||::||:||||||:|||.||||||:||||||||::|:. ||.|.|.
  Fly     1 MNEEYDAIVLGTGLKECILSGMLSVSGKKVLHIDRNKYYGGESASITPLEELFQRYG-LEPPGER 64

Human    66 MGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVPSTETEALASN 130
            .|||||||||||||||||||||||:|::|.|||||:||.:|||:|||||||.|||..:.|||||:
  Fly    65 FGRGRDWNVDLIPKFLMANGQLVKLLIHTGVTRYLEFKSIEGSYVYKGGKIAKVPVDQKEALASD 129

Human   131 LMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQTTSMRDVYRKFDLGQDVIDFTGHALALYRTD 195
            |||||||||||.||::|.:|.|:||||::..||...:|:.:|.||.|.::..|||||||||:|.|
  Fly   130 LMGMFEKRRFRNFLIYVQDFREDDPKTWKDFDPTKANMQGLYDKFGLDKNTQDFTGHALALFRDD 194

Human   196 DYLDQPCLETVNRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPVDDIIM 260
            :||::|.:.|:.||||||:|||||||||||||:|||||||||||||||||||||||:||:|:|::
  Fly   195 EYLNEPAVNTIRRIKLYSDSLARYGKSPYLYPMYGLGELPQGFARLSAIYGGTYMLDKPIDEIVL 259

Human   261 -ENGKVVGVKSEGEVARCKQLICDPSYIPDRVRKAGQVIRIICILSHPIKNTNDANSCQIIIPQN 324
             |.||||||:|..|||:|||:.|||||:|::|||.|:|||.||||.||:.:|.|..|.||||||.
  Fly   260 GEGGKVVGVRSGEEVAKCKQVYCDPSYVPEKVRKRGKVIRCICILDHPVASTKDGLSTQIIIPQK 324

Human   325 QVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVETTDPEKEVEPALELLEPIDQKFVAISDLYEP 389
            ||.|||||||.::|..|.|||:|.::.:.||||||.:||.|::|.|:|||||.||||.|||..||
  Fly   325 QVGRKSDIYVSLVSSTHQVAAKGWFVGMVSTTVETENPEVEIKPGLDLLEPIAQKFVTISDYLEP 389

Human   390 IDDGCESQVFCSCSYDATTHFETTCNDIKDIYKRMAGTAFDFENMKRKQNDVFGEAEQ 447
            ||||.|||:|.|.||||||||||||.|:.:|:||..|..|||..:|.:    .|:.||
  Fly   390 IDDGSESQIFISESYDATTHFETTCLDVLNIFKRGTGETFDFSKIKHE----LGDEEQ 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GDI1	NP_001484.1	GDI	1..436	CDD:395792	297/435 (68%)
Gdi	NP_523524.2	GDI	1..435	CDD:395792	297/434 (68%)