Protein Alignment GDF10 and scw

DIOPT Version :9

• Sequence 1: NP_004953.1
• Gene: GDF10 / 2662
• HGNCID: 4215
• Length: 478
• Species: Homo sapiens
• Sequence 2: NP_001286088.1
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Alignment Length: 398
• Identity: 85/398 - (21%)
• Similarity: 137/398 - (34%)
• Gaps: 126/398 - (31%)

Human    97 NTVRSFRARL--EVVDQKAVYF--FNLTSMQDSEMILTATFHFYSEPPRWPRALEVLCKPRAKNA 157
            |::.:|.:||  |.:|.:....  ||...:.....::.|....|.:|....|..........|
  Fly   111 NSILTFSSRLKPEQLDNELDMHITFNTNDVPVDLSLVQAMLRIYKQPSLVDRRANFTVSVYRK-- 173

Human   158 SGRPLPLGPPTRQHLLFRSL-SQNTATQGLLRGAMALAPPPRGLWQAKDISPIV------KAARR 215
                    ...||...:|.| |.||.:.            .|| |...:::..:      |..:|
  Fly   174 --------LDNRQDFSYRILGSVNTTSS------------QRG-WLEFNLTDTLRYWLHNKGLQR 217

Human   216 DGELLLS---AQLDSEERDPGVPRPS--PYAPYILVYANDLAISEPNSVAVTLQRYDPFPAGDPE 275
            ..||.:|   :||.:.......|:.|  ...|:|:.|.|...:    .|.:...|:    ..|.|
  Fly   218 RNELRISIGDSQLSTFAAGLVTPQASRTSLEPFIVGYFNGPEL----LVKIQKLRF----KRDLE 274

Human   276 PRAAPNNSADPRVRRAAQATGPLQDNELPGLDERPPRAHAQHFHKHQLWPSPFRALKPRPGRKDR 340
            .|.|...|..|                       ||             |.|....:|
  Fly   275 KRRAGGGSPPP-----------------------PP-------------PPPVDLYRP------- 296

Human   341 RKKGQEVFMAASQVLDFDEKTMQKARRKQWDEPRVCSRRYLKVDFADIGWNEWIISPKSFDAYYC 405
                                            |:.|.|....|||.::..:.|:|:||.|:||:|
  Fly   297 --------------------------------PQSCERLNFTVDFKELHMHNWVIAPKKFEAYFC 329

Human   406 AGACEFPMPKIVRPSNHATIQSIVRAVGIIPGIPEPCCVPDKMNSLGVL-FLDENRNVVLKVYPN 469
            .|.|.||:...:..:|||.:|:::....  |.:|:|||||..:.::.:| :|:|: .:.|..|..
  Fly   330 GGGCNFPLGTKMNATNHAIVQTLMHLKQ--PHLPKPCCVPTVLGAITILRYLNED-IIDLTKYQK 391

Human   470 MSVDTCAC 477
            .....|.|
  Fly   392 AVAKECGC 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GDF10	NP_004953.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	266..319		8/52 (15%)
		TGF_beta	374..477	CDD:278448	34/103 (33%)
scw	NP_001286088.1	TGFb_propeptide	39..254	CDD:279078	34/165 (21%)
		TGFB	300..400	CDD:214556	35/103 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810