Protein Alignment BSCL2 and seip-1

DIOPT Version :10

• Sequence 1: NP_001372956.1
• Gene: BSCL2 / 26580
• HGNCID: 15832
• Length: 464
• Species: Homo sapiens
• Sequence 2: NP_741547.1
• Gene: seip-1 / 259621
• WormBaseID: WBGene00019808
• Length: 274
• Species: Caenorhabditis elegans
• Alignment Length: 280
• Identity: 67/280 - (23%)
• Similarity: 120/280 - (42%)
• Gaps: 28/280 - (10%)

Human    93 LQFGV-LFCTILLLLWVSVFLYG----SFYYSYMP-TVSHLSPVHFYYRTDCDSSTTSLCSFPVA 151
            ::||. .|.:.|:.|.|::|:..    ...|..:| :|.|...::..::| ||....|:||||.|
 Worm     1 MRFGKDCFLSTLVELSVAIFIAAVTPLLIRYCLLPSSVHHQYQLNIVFQT-CDHDLHSVCSFPAA 64

Human   152 NVSLTKGGRDRVLMYGQPYRVTLELELPESPVNQDLGMFLVTISCYTRGGRIISTSSRSVMLHYR 216
            .:...|   :.:......|.:.:.|:..:......||:|...|:......:|:...::|..:. .
 Worm    65 TLEYEK---NSLFSPNVAYYLNVRLKFADVINTNKLGLFQNVITITDENQKILKQYTKSAYVK-E 125

Human   217 SDLLQMLDTLVFSSLLLFGFAEQKQLLEVELYADYRENSYVPTTGAIIEIHSKRIQLYGAYLRIH 281
            :.|:|....|........||......|.:.:.|||.|....|:|..:..:..|...:..|.|.:.
 Worm   126 AGLIQKAMHLFLFPFYFLGFFHDYSTLAIPMSADYLEGIDSPSTKLVFVVQDKFANIEEAELIVT 190

Human   282 AHFTGLRYLLYNFPMTCAFIGVASNF---TFLSVIVLFSYMQWVWGGIWPRHRFSLQVNIRKRD- 342
            |.|..:|:|||.:|.|.......|.|   .|| ::....|.::.     .|.|..|:   ::::
 Worm   191 ARFGLIRHLLYYWPTTSYATIFVSTFVIGVFL-IMTKIGYQEYT-----ARTRAILE---KEKEE 246

Human   343 ----NSRKEVQRRISAHQPG 358
                :|.|||::.|...:||
 Worm   247 LSPRSSEKEVKKEIKKEEPG 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BSCL2	NP_001372956.1	Seipin	122..286	CDD:467827	38/164 (23%)
		PHA03169	<355..>414	CDD:223003	2/4 (50%)
seip-1	NP_741547.1	Seipin	16..216	CDD:462007	48/204 (24%)