Protein Alignment BSCL2 and Bscl2

DIOPT Version :10

• Sequence 1: NP_001372956.1
• Gene: BSCL2 / 26580
• HGNCID: 15832
• Length: 464
• Species: Homo sapiens
• Sequence 2: NP_032170.3
• Gene: Bscl2 / 14705
• MGIID: 1298392
• Length: 443
• Species: Mus musculus
• Alignment Length: 459
• Identity: 387/459 - (84%)
• Similarity: 410/459 - (89%)
• Gaps: 17/459 - (3%)

Human     6 VDQKEEAGEKEVCGDQIKGPDKEEEPPAAASHGQGWRPGGRAARNARPEPGARHPALPAMVNDPP 70
            :.|:.|||.:|.|.|||||.||:|||.||.|||||:||.||.|||::||.|||.||:|.||||||
Mouse     2 IHQRREAGARETCRDQIKGSDKDEEPSAALSHGQGYRPCGRPARNSKPEAGARPPAVPIMVNDPP 66

Human    71 VPALLWAQEVGQVLAGRARRLLLQFGVLFCTILLLLWVSVFLYGSFYYSYMPTVSHLSPVHFYYR 135
            |||||||||||.|||||||||:||||||||||||||||||||||||||||||||||||||||:||
Mouse    67 VPALLWAQEVGHVLAGRARRLMLQFGVLFCTILLLLWVSVFLYGSFYYSYMPTVSHLSPVHFHYR 131

Human   136 TDCDSSTTSLCSFPVANVSLTKGGRDRVLMYGQPYRVTLELELPESPVNQDLGMFLVTISCYTRG 200
            |||||||.||||||||||||.|.|||||||||||||||||||||||||||||||||||:||||||
Mouse   132 TDCDSSTASLCSFPVANVSLAKSGRDRVLMYGQPYRVTLELELPESPVNQDLGMFLVTVSCYTRG 196

Human   201 GRIISTSSRSVMLHYRSDLLQMLDTLVFSSLLLFGFAEQKQLLEVELYADYRENSYVPTTGAIIE 265
            |||||||||||||||||.|||:||||:|||||||||||||||||||||:||||||||||||||||
Mouse   197 GRIISTSSRSVMLHYRSQLLQVLDTLLFSSLLLFGFAEQKQLLEVELYSDYRENSYVPTTGAIIE 261

Human   266 IHSKRIQLYGAYLRIHAHFTGLRYLLYNFPMTCAFIGVASNFTFLSVIVLFSYMQWVWGGIWPRH 330
            |||||||:|||||||||||||||||||||||||||:|||||||||||||||||||||||.:||||
Mouse   262 IHSKRIQMYGAYLRIHAHFTGLRYLLYNFPMTCAFVGVASNFTFLSVIVLFSYMQWVWGAVWPRH 326

Human   331 RFSLQVNIRKRDNSRKEVQRRISAHQPGAGPEGQEESTPQSDVTEDGESPEDPSGTEGQLSEEEK 395
            |||||||||:||||.....||||.||||      :|||.||||||||||||||||||||||||||
Mouse   327 RFSLQVNIRQRDNSHHGAPRRISRHQPG------QESTQQSDVTEDGESPEDPSGTEGQLSEEEK 385

Human   396 PDQQPLSGEEELEPEASDGSGSWEDAALLTEANLPAPAPASASAPVLETLGSSEPAGGALRQRPT 460
            |:::||:||||.||||||  |||||||||||||.|..|.|||.||  |||||       ||||||
Mouse   386 PEKRPLNGEEEQEPEASD--GSWEDAALLTEANPPTSASASALAP--ETLGS-------LRQRPT 439

Human   461 CSSS 464
            ||||
Mouse   440 CSSS 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BSCL2	NP_001372956.1	Seipin	122..286	CDD:467827	153/163 (94%)
		PHA03169	<355..>414	CDD:223003	45/58 (78%)
Bscl2	NP_032170.3	Seipin	99..303	CDD:462007	192/203 (95%)
		PTZ00415	345..>409	CDD:185603	54/71 (76%)