DRSC/TRiP Functional Genomics Resources

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Protein Alignment OPN1MW and Opn1mw

DIOPT Version :9

Sequence 1:NP_000504.1 Gene:OPN1MW / 2652 HGNCID:4206 Length:364 Species:Homo sapiens
Sequence 2:NP_032132.1 Gene:Opn1mw / 14539 MGIID:1097692 Length:359 Species:Mus musculus


Alignment Length:357 Identity:315/357 - (88%)
Similarity:336/357 - (94%) Gaps:0/357 - (0%)


- Green bases have known domain annotations that are detailed below.


Human     8 QRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWMIFVVIASVFTNG 72
            |||.|....|.|||||.:|||||||||||:||||||||||||||||||||.|||.||:|||||||
Mouse     3 QRLTGEQTLDHYEDSTHASIFTYTNSNSTKGPFEGPNYHIAPRWVYHLTSTWMILVVVASVFTNG 67

Human    73 LVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISVVNQVYGYFVLGHPMCVLEGYTVSLCG 137
            |||||||:|||||||||||||||||||||||:||||||||||:|||||||||:||:|||.|||||
Mouse    68 LVLAATMRFKKLRHPLNWILVNLAVADLAETIIASTISVVNQIYGYFVLGHPLCVIEGYIVSLCG 132

Human   138 ITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIVGIAFSWIWAAVWTAPPIFGWSRYWPHGLKTS 202
            |||||||||||||||:||||||||||||||||.|||.|||:|||:||||||||||||||:|||||
Mouse   133 ITGLWSLAIISWERWLVVCKPFGNVRFDAKLATVGIVFSWVWAAIWTAPPIFGWSRYWPYGLKTS 197

Human   203 CGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIRAVAKQQKESESTQKAEKEVT 267
            ||||||||:|||||||||:||||||||.|||||||||||||||||||||||||||||||||||||
Mouse   198 CGPDVFSGTSYPGVQSYMMVLMVTCCIFPLSIIVLCYLQVWLAIRAVAKQQKESESTQKAEKEVT 262

Human   268 RMVVVMVLAFCFCWGPYAFFACFAAANPGYPFHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNC 332
            |||||||.|:|.|||||.||||||.|:|||.||||:|:||::||||||||||:||||||||||||
Mouse   263 RMVVVMVFAYCLCWGPYTFFACFATAHPGYAFHPLVASLPSYFAKSATIYNPIIYVFMNRQFRNC 327

Human   333 ILQLFGKKVDDGSELSSASKTEVSSVSSVSPA 364
            ||.||||||||.|||||.||||||||||||||
Mouse   328 ILHLFGKKVDDSSELSSTSKTEVSSVSSVSPA 359

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
OPN1MWNP_000504.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..23 8/14 (57%)
Required for 11-cis-retinal regeneration. /evidence=ECO:0000269|PubMed:30948514 17..43 21/25 (84%)
7tm_4 61..>178 CDD:304433 105/116 (91%)
7tm_1 71..322 CDD:278431 223/250 (89%)
Opn1mwNP_032132.1 Required for 11-cis-retinal regeneration. /evidence=ECO:0000250|UniProtKB:P04001 12..38 21/25 (84%)
7tm_1 66..317 CDD:278431 223/250 (89%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C83961051
Domainoid 1 1.000 496 1.000 Domainoid score I7820
eggNOG 1 0.900 - - E33208_3BF9S
HGNC 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 675 1.000 Inparanoid score I9556
Isobase 00.000 Not matched by this tool.
NCBI 1 1.000 - -
OMA 1 1.010 - - QHG39757
OrthoDB 1 1.010 - - D400545at33208
OrthoFinder 1 1.000 - - FOG0006379
OrthoInspector 1 1.000 - - otm51775
orthoMCL 1 0.900 - - OOG6_111679
Panther 1 1.100 - - LDO PTHR24240
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R6204
SonicParanoid 1 1.000 - - X120
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
1615.840

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