DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CHIC2 and CG5938

DIOPT Version :9

Sequence 1:	NP_036242.1	Gene:	CHIC2 / 26511	HGNCID:	1935	Length:	165	Species:	Homo sapiens
Sequence 2:	NP_001097947.2	Gene:	CG5938 / 43290	FlyBaseID:	FBgn0046247	Length:	168	Species:	Drosophila melanogaster

Alignment Length:	165	Identity:	106/165 - (64%)
Similarity:	140/165 - (84%)	Gaps:	1/165 - (0%)

- Green bases have known domain annotations that are detailed below.

Human     2 ADFDEIYEEEE-DEERALEEQLLKYSPDPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVAPEEFK 65
            :|||.|||:|: ||....::|.:....:|:::||:|::|||||||:|.:|||..|..:|||||||
  Fly     4 SDFDAIYEDEQLDELEHFQDQTVAPVQEPIIIRGAGNMTVFGLSNRFNAEFPCGLLSRVAPEEFK 68

Human    66 ASINRVNSCLKKNLPVNVRWLLCGCLCCCCTLGCSMWPVICLSKRTRRSIEKLLEWENNRLYHKL 130
            |::.|:|..|||:|||||:||.|||:|||||||||:||||||||||:.:::||.|||||.|||||
  Fly    69 ATVGRINGVLKKSLPVNVKWLFCGCVCCCCTLGCSLWPVICLSKRTQLTLDKLFEWENNHLYHKL 133

Human   131 CLHWRLSKRKCETNNMMEYVILIEFLPKTPIFRPD 165
            .|||||.|::|::|:||||||||||:|||||:|||
  Fly   134 GLHWRLHKQQCDSNSMMEYVILIEFIPKTPIYRPD 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CHIC2	NP_036242.1	Erf4	46..134	CDD:402047	60/87 (69%)
CHIC2	NP_036242.1	CHIC motif (Cys-rich)	88..106		15/17 (88%)
CG5938	NP_001097947.2	Erf4	49..137	CDD:287258	60/87 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141026
Domainoid	1	1.000	153	1.000	Domainoid score	I4290
eggNOG	1	0.900	-	-		E1_KOG4101
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8105
Inparanoid	1	1.050	249	1.000	Inparanoid score	I3246
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47997
OrthoDB	1	1.010	-	-		D1449345at2759
OrthoFinder	1	1.000	-	-		FOG0003641
OrthoInspector	1	1.000	-	-		otm41102
orthoMCL	1	0.900	-	-		OOG6_105429
Panther	1	1.100	-	-	LDO	PTHR13005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2509
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.770