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Protein Alignment SLC17A5 and CG12490

DIOPT Version :10

Sequence 1:	NP_001369562.1	Gene:	SLC17A5 / 26503	HGNCID:	10933	Length:	533	Species:	Homo sapiens
Sequence 2:	NP_611722.2	Gene:	CG12490 / 37623	FlyBaseID:	FBgn0034782	Length:	479	Species:	Drosophila melanogaster

Alignment Length:	450	Identity:	129/450 - (28%)
Similarity:	220/450 - (48%)	Gaps:	46/450 - (10%)

- Green bases have known domain annotations that are detailed below.

Human    17 TDRTPLLPGAPRAEAAPVCCSARYNLAILAFFGFFIVYALRVNLSVALVDMVDSNTTLEDNRTSK 81
            |::.|:|             ..|:..|:|.|.....|:..|:|:.|::|.|.::.||
  Fly     5 TNKGPVL-------------GMRHVQALLIFLNITTVFIGRLNVGVSVVAMTNAETT-------- 48

Human    82 ACPEHSAPIKVHHNQTGKKYQWDAETQGWILGSFFYGYIITQIPGGYVASKIGGKMLLGFGILGT 146
                         |....:|.|....:.:|..|||:|||:||..|||:..:.|.|.::.:|:..:
  Fly    49 -------------NPNFPEYDWTEAEKSYIFSSFFWGYILTQFIGGYLCKRFGVKSVMFWGVFVS 100

Human   147 AVLTLFTPIAADLGVG---PLIVLRALEGLGEGVTFPAMHAMWSSWAPPLERSKLLSISYAGAQL 208
            .|.:..||:.  :|.|   ....:|.:.||.:|:.||.:|...:.|:||.||::|.::|:.|.:.
  Fly   101 GVCSALTPLF--IGFGGWQAYCGIRVVMGLAQGLVFPCIHHHLAKWSPPAERNRLGALSHTGMEC 163

Human   209 GTVISLPLSGIIC-YYMNWTYVFYFFGTIGIFWFLLWIWLVSDTPQKHKRISHYEKEYILSSLRN 272
            |.|.::.|||:|. ..:.|..:.|....:...|..:|....:|...:.:.|:..|..||.|||::
  Fly   164 GNVSAMFLSGMIAKSAIGWPGISYVSAGLAFAWCAIWFVFAADNAVESRYITQEELHYIESSLKH 228

Human   273 QLSSQKS---VPWVPILKSLPLWAIVVAHFSYNWTFYTLLTLLPTYMKEILRFNVQENGFLSSLP 334
            .....|:   |||:.|..|.|..|:.:......|...||...:||||..:|..:::.|.|.|:||
  Fly   229 NEDYHKTVIPVPWMAIWTSAPFLALTLTRCCATWGLSTLQAQIPTYMNGVLDMDMKSNAFFSALP 293

Human   335 YLGSWLCMILSGQAADNLRAKWNFSTLCVRRIFSLIGMIGPAVFLVAAGFIGCDY-SLAVAFLTI 398
            :|..|:...:....||.|.|....|...:|:.|:.:....|...|:..||:..:. :||:|.:||
  Fly   294 FLAMWIMSYVYLIIADVLLAGNRLSLTALRKTFNSLAFWIPCATLIGIGFLDQEQKNLAIALMTI 358

Human   399 STTLGGFCSSGFSINHLDIAPSYAGILLGITNTFATIPGMVGPVIAKSLT--PDAGVQWR 456
            |..:....:.|.|:|.:|::|::|.||:||.||..|:..:|.|:|...:.  .|...:|:
  Fly   359 SVGVNSGATIGSSLNTIDLSPNHASILMGILNTAVTVVPIVTPLIVGVIVHEDDNRAEWQ 418

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.