Protein Alignment PTPN18 and CG42327

DIOPT Version :9

• Sequence 1: XP_006712480.1
• Gene: PTPN18 / 26469
• HGNCID: 9649
• Length: 464
• Species: Homo sapiens
• Sequence 2: NP_001036706.2
• Gene: CG42327 / 41401
• FlyBaseID: FBgn0259227
• Length: 1429
• Species: Drosophila melanogaster
• Alignment Length: 333
• Identity: 103/333 - (30%)
• Similarity: 148/333 - (44%)
• Gaps: 81/333 - (24%)

Human    29 EFSDIQACSAAWKADGVCSTVAGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIR 93
            ||.|:....|  :||.|       .|....||||.:|:|..:|||:|....::..::|||.|::|
  Fly  1114 EFRDVPQIIA--RADEV-------PPGCEDKNRYANVIPLPETRVVLQRQGDDDKTEYINANYVR 1169

Human    94 GV-DGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQEPLQT--- 154
            |. |....|||.|.||..|..||||::||...:||:.|....|||.:||..|    ..|..|
  Fly  1170 GPRDAPNYYIACQAPLESTTSDFWRMIWEQQSRVIIQATDLSENGIERCAEY----LPPSATLDN 1230

Human   155 ----GLFCITL----IKEKWLNEDIMLRTLKVTFQKESRSVYQLQYMSWPDRGVPSSPDHMLAMV 211
                |.:.:||    :|:::....::|:.:.   .:|||.:....| .||:.|||:....::||:
  Fly  1231 HSSYGDYQVTLKHREVKDRYAISTLVLKRVD---GEESRELTHYWY-KWPEAGVPAEEAPIIAML 1291

Human   212 EEARR-------------------------LQGSGPE------------------------PLCV 227
            .|||.                         ..||..|                        ||.|
  Fly  1292 LEARSSLKSYSLEQANELREKSATLETSMDADGSKAEAGSTSSHEINGNISSRSGTRSQQGPLTV 1356

Human   228 HCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQMF 292
            |||.|.||||.:...|...:.|.|.....|..  .:|..:|:.|.:||||:|||.|:| .||.|:
  Fly  1357 HCSPGTGRTGTIIASDMAIRSLETPKRSVDIP--QLVYYVRRGRASAVQTKEQYEFIY-KVASMY 1418

Human   293 CSTLQNAS 300
            .:.:.|.|
  Fly  1419 AAKITNLS 1426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTPN18	XP_006712480.1	Y_phosphatase	56..290	CDD:278528	91/294 (31%)
		PTPc	59..290	CDD:238006	91/291 (31%)
CG42327	NP_001036706.2	PTPc	1134..1415	CDD:238006	90/291 (31%)
		Y_phosphatase	1134..1415	CDD:278528	90/291 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810