Protein Alignment Nr5a1 and ftz-f1

DIOPT Version :9

• Sequence 1: NP_001303616.1
• Gene: Nr5a1 / 26423
• MGIID: 1346833
• Length: 462
• Species: Mus musculus
• Sequence 2: NP_524143.2
• Gene: ftz-f1 / 40045
• FlyBaseID: FBgn0001078
• Length: 1027
• Species: Drosophila melanogaster
• Alignment Length: 538
• Identity: 197/538 - (36%)
• Similarity: 268/538 - (49%)
• Gaps: 103/538 - (19%)

Mouse    10 DELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCL 74
            :|||||||||||||||||||||||||||||||||.|.|||...:||.||||||||||:|||||||
  Fly   505 EELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCL 569

Mouse    75 TVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQ--KKAQIRANGFKLETGPPMGVPPPPPPP-- 135
            .|||:|||||||||||||||||||||||||.|.|  ::.|:.....:...||  .:.|.|..|
  Fly   570 EVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRNSMGP--DIKPTPISPGY 632

Mouse   136 ----PDYMLPPSLHAPEPKALVSGPPSGP------LGDF-----GAPSLPM----------AVPG 175
                |:..:...:..|:..:|...|.|.|      ||..     |..:.||          .:.|
  Fly   633 QQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASTGGVIATPMNAGTGGSGGGGLNG 697

Mouse   176 PHGPLAGYLYPAFSN-------------------------------------------------- 190
            |.....|......||
  Fly   698 PSSVGNGNSSNGSSNGNNNSSTGNGTSGGGGGNNAGGGGGGTNSNDGLHRNGGNGNSSCHEAGIG 762

Mouse   191 ---RTIKSEYPEPYASPPQQPGPPYSYPEPFSGGPNVPELILQLLQLEPEEDQVRARIVGCLQEP 252
               .|..|:......:.|.....  :..||....|.:.|.:..:     ::.:.:.::...||:.
  Fly   763 SLQNTADSKLCFDSGTHPSSTAD--ALIEPLRVSPMIREFVQSI-----DDREWQTQLFALLQKQ 820

Mouse   253 AKSRSDQPAPFSLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVLDHIYRQVQ 317
            ..::.:... |.|:|::.||...|.|||||..:.||:|:|.|||.|||:.||::|||||::.::.
  Fly   821 TYNQVEVDL-FELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIH 884

Mouse   318 YGKEDSILLVTGQEVELSTVAV----QAGSLLHSLVLRAQELVLQLHALQLDRQEFVCLKFLILF 378
            .|..|...|..||...|.::.:    |.|...:       ||..:|..|:.|..::||:|||||.
  Fly   885 NGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFN-------ELQNKLQDLKFDMGDYVCMKFLILL 942

Mouse   379 SLDVKFLNNHSLVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHL 443
            :..|:.:.|...|.:..:...||||||||..||...|||:.|:..|.|:.|::::.:::||.||.
  Fly   943 NPSVRGIVNRKTVSEGHDNVQAALLDYTLTCYPSVNDKFRGLVNILPEIHAMAVRGEDHLYTKHC 1007

Mouse   444 GNEMPRNNLLIEMLQAKQ 461
            ....|...||:|||.||:
  Fly  1008 AGSAPTQTLLMEMLHAKR 1025

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nr5a1	NP_001303616.1	NR_DBD_Lrh-1_like	13..105	CDD:143541	81/91 (89%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	117..149		7/37 (19%)
		MISS	<147..217	CDD:292450	18/143 (13%)
		NR_LBD_SF-1	237..460	CDD:132755	80/226 (35%)
ftz-f1	NP_524143.2	NR_DBD_Lrh-1_like	508..600	CDD:143541	81/91 (89%)
		NR_LBD_Ftz-F1_like	794..1024	CDD:132742	82/242 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847183
Domainoid	1	1.000	144	1.000	Domainoid score	I4586
eggNOG	1	0.900	-	-		E1_KOG4218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	375	1.000	Inparanoid score	I2064
Isobase	1	0.950	-	0	Normalized mean entropy	S5899
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D278717at33208
OrthoFinder	1	1.000	-	-		FOG0002223
OrthoInspector	1	1.000	-	-		otm43073
orthoMCL	1	0.900	-	-		OOG6_105772
Panther	1	1.100	-	-	O	PTHR24086
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2678
SonicParanoid	1	1.000	-	-		X1468
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.740