Protein Alignment Mapk3 and p38b

DIOPT Version :9

• Sequence 1: NP_036082.1
• Gene: Mapk3 / 26417
• MGIID: 1346859
• Length: 380
• Species: Mus musculus
• Sequence 2: NP_477361.1
• Gene: p38b / 34780
• FlyBaseID: FBgn0024846
• Length: 365
• Species: Drosophila melanogaster
• Alignment Length: 348
• Identity: 163/348 - (46%)
• Similarity: 240/348 - (68%)
• Gaps: 18/348 - (5%)

Mouse    37 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLRFRHEN 100
            :::...|..||.:|:||||.|..|......|:|||||:: ||:...:.:||.||:::|....|||
  Fly    18 WEIPETYQNLQPVGQGAYGQVCKAVVRGTSTKVAIKKLARPFQSAVHAKRTYRELRLLKHMDHEN 82

Mouse   101 VIGIRDILR----APTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSA 161
            |||:.|:..    |.:|:..:.||:|..||:.||..::::|:||:||:.:.:|||||||||||||
  Fly    83 VIGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLNNIIRTQKLSDDHVQFLVYQILRGLKYIHSA 147

Mouse   162 NVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKS 226
            .|:||||||||:.:|..|:|:|.||||||.|:.|      :|.|||||||||||||||...|.::
  Fly   148 GVIHRDLKPSNIAVNEDCELRILDFGLARPAESE------MTGYVATRWYRAPEIMLNWMHYNQT 206

Mouse   227 IDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKV 291
            .||||||||:||:|:.|.:|||..::.|||.|:.:||:|:.|.::.|.:..||||::|||...:.
  Fly   207 ADIWSVGCIMAELLTGRTLFPGTDHIHQLNLIMEVLGTPADEFMSRISSESARNYIRSLPVMPRR 271

Mouse   292 AWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVA---EEPFTFDMEL 353
            .:..:|..::..|:|||::||..:.:||||.|:||||||:|:|:|||||..|   ::.|    |.
  Fly   272 NFRDIFRGANPLAIDLLEKMLELDADKRITAEQALAHPYMEKYHDPTDEQTAALYDQSF----EE 332

Mouse   354 DDLPKERLKELIFQETARFQPGA 376
            ::||.|:.:|::|.|...|:|.|
  Fly   333 NELPVEKWREMVFSEVTAFKPTA 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mapk3	NP_036082.1	STKc_ERK1_2_like	37..371	CDD:270839	160/341 (47%)
		TXY	203..205		1/1 (100%)
p38b	NP_477361.1	STKc_p38	8..353	CDD:143356	161/344 (47%)
		S_TKc	24..311	CDD:214567	143/292 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0660
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810