Protein Alignment GCG and STE13

DIOPT Version :10

• Sequence 1: NP_002045.1
• Gene: GCG / 2641
• HGNCID: 4191
• Length: 180
• Species: Homo sapiens
• Sequence 2: NP_014862.3
• Gene: STE13 / 854394
• SGDID: S000005745
• Length: 931
• Species: Saccharomyces cerevisiae
• Alignment Length: 191
• Identity: 39/191 - (20%)
• Similarity: 66/191 - (34%)
• Gaps: 69/191 - (36%)

Human     7 VAGLFVMLVQ-------------GSWQRSL------QDTEEKSRSFSASQADPLSDPDQMNEDK- 51
            |:||.|:::|             .||.|..      :|..|.::.|....:      ..::|.|
Yeast   721 VSGLDVIVLQIEPRGTGGKGWSFRSWAREKLGYWEPRDITEVTKKFIQRNS------QHIDESKI 779

Human    52 ---RHSQGTFTS---------DYSKYLDSRRAQDFVQWLM----NTKRNRNNIAKRHDEFERHAE 100
               ..|.|.|||         |..||  :........|.:    .|:|..|..::.|       |
Yeast   780 AIWGWSYGGFTSLKTVELDNGDTFKY--AMAVAPVTNWTLYDSVYTERYMNQPSENH-------E 835

Human   101 GTF-TSDVSSYLEGQAAKEFIAWLVKGRGRRDFPEEVAIVEELGRRHADGSFS--DEMNTI 158
            |.| .|.:.::...::.|..  ::|.|    .|.:.|         |...:|.  |::|.:
Yeast   836 GYFEVSTIQNFKSFESLKRL--FIVHG----TFDDNV---------HIQNTFRLVDQLNLL 881

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GCG	NP_002045.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	26..59		6/36 (17%)
		Hormone_2	53..80	CDD:459681	9/39 (23%)
		Hormone_2	98..125	CDD:459681	5/27 (19%)
		Hormone_2	146..173	CDD:459681	4/15 (27%)
STE13	NP_014862.3	DPPIV_N	247..623	CDD:395744
		Peptidase_S9	713..919	CDD:459761	39/191 (20%)