Protein Alignment GCG and gcg

DIOPT Version :9

• Sequence 1: NP_002045.1
• Gene: GCG / 2641
• HGNCID: 4191
• Length: 180
• Species: Homo sapiens
• Sequence 2: NP_001006913.1
• Gene: gcg / 448760
• XenbaseID: XB-GENE-1000156
• Length: 266
• Species: Xenopus tropicalis
• Alignment Length: 261
• Identity: 99/261 - (37%)
• Similarity: 143/261 - (54%)
• Gaps: 83/261 - (31%)

Human     1 MKSIYFVAGLFVMLVQGSWQRSLQDTEEKSRSFSASQADPLSDPDQMNEDKRHSQGTFTSDYSKY 65
            |||.|::.|:.:|::..::|..:.:|:..|||..|::.:.:.|..|:.|.|||||||||||||||
 Frog     1 MKSTYYMIGILLMILHNTYQSPVPETDASSRSVKAARNEAVDDSQQLKEVKRHSQGTFTSDYSKY 65

Human    66 LDSRRAQDFVQWLMNTKRN---------------------------------------------- 84
            |||||||||:||||||||:
 Frog    66 LDSRRAQDFIQWLMNTKRSGGLSRRNADYERHAEGTFTSDVTQHLDEKAAKEFIDWLINGGPSKE 130

Human    85 ----RNNIAKRHDE--------------------------------FERHAEGTFTSDVSSYLEG 113
                ||...:||.|                                :.||||||||:|:::|||.
 Frog   131 IISRRNADVERHAEGTYTNDVTEYLEEKAAKEFIEWLINGKPKKIRYSRHAEGTFTNDMTNYLEE 195

Human   114 QAAKEFIAWLVKGRGRRDFPEEVAIVEELGRRHADGSFSDEMNTILDNLAARDFINWLIQTKITD 178
            :|||||:.||:|||.:|:| .|...|||:.||||||||::::|.:||.:||::|::|:|.|::|:
 Frog   196 KAAKEFVGWLIKGRPKRNF-SEAHSVEEMDRRHADGSFTNDINKVLDIIAAQEFLDWVINTQVTE 259

Human   179 R 179
            |
 Frog   260 R 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GCG	NP_002045.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	26..59		15/32 (47%)
		Hormone_2	53..80	CDD:395073	25/26 (96%)
		Hormone_2	98..124	CDD:395073	17/25 (68%)
		Hormone_2	146..173	CDD:395073	13/26 (50%)
gcg	NP_001006913.1	Hormone_2	53..80	CDD:365889	25/26 (96%)
		Hormone_2	97..124	CDD:365889	0/26 (0%)
		Hormone_2	142..169	CDD:365889	2/26 (8%)
		Hormone_2	180..207	CDD:365889	18/26 (69%)
		Hormone_2	227..254	CDD:365889	13/26 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	63	1.000	Domainoid score	I37611
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	176	1.000	Inparanoid score	I12334
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG41657
OrthoDB	1	1.010	-	-		D1349644at2759
OrthoFinder	1	1.000	-	-		FOG0007968
OrthoInspector	1	1.000	-	-		oto157469
Panther	1	1.100	-	-	LDO	PTHR11418
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6741
SonicParanoid	1	1.000	-	-		X9991
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110