DRSC/TRiP Functional Genomics Resources

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Protein Alignment GCG and CG45002

DIOPT Version :10

Sequence 1:NP_002045.1 Gene:GCG / 2641 HGNCID:4191 Length:180 Species:Homo sapiens
Sequence 2:NP_728041.3 Gene:CG45002 / 32688 FlyBaseID:FBgn0266354 Length:1098 Species:Drosophila melanogaster


Alignment Length:152 Identity:29/152 - (19%)
Similarity:59/152 - (38%) Gaps:47/152 - (30%)


- Green bases have known domain annotations that are detailed below.


Human    44 PDQMNE-----DKRHSQGTFTSD-----YSKYLDSRRAQDFVQWLMNTKRNRNNIAKRHDEFERH 98
            ||.|.|     :.|.|...|:.|     :..|.||...:....|:.:..:....:::|:.:    
  Fly   323 PDWMYENVPELESRRSSMEFSPDGLFLAFLSYNDSEVNEYKYTWMGDDIKYPAVMSQRYPK---- 383

Human    99 AEGTFTSDVSSYLEGQAAKEFIAWLVKGRGRRDFPEEVAIVEELGRRHADGSF--------SDEM 155
             .|:...:|:..:...:..::|           ||.::.:..||    ::||:        |.::
  Fly   384 -TGSRNPNVTVNVVNLSVIKYI-----------FPTQIKLPSEL----SNGSYVGGLTWASSTDL 432

Human   156 NTILDNLAARDFINWLIQTKIT 177
            :..:.|   |:      |||.|
  Fly   433 SVTVTN---RE------QTKAT 445

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GCGNP_002045.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 26..59 6/19 (32%)
Hormone_2 53..80 CDD:459681 7/31 (23%)
Hormone_2 98..125 CDD:459681 3/26 (12%)
Hormone_2 146..173 CDD:459681 5/34 (15%)
CG45002NP_728041.3 DPPIV_N 278..681 CDD:395744 29/152 (19%)
Peptidase_S9 765..969 CDD:459761
Blue background indicates that the domain is not in the aligned region.

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