Protein Alignment Map3k7 and slpr

DIOPT Version :9

• Sequence 1: NP_033342.1
• Gene: Map3k7 / 26409
• MGIID: 1346877
• Length: 606
• Species: Mus musculus
• Sequence 2: NP_001188558.1
• Gene: slpr / 44111
• FlyBaseID: FBgn0030018
• Length: 1155
• Species: Drosophila melanogaster
• Alignment Length: 657
• Identity: 167/657 - (25%)
• Similarity: 264/657 - (40%)
• Gaps: 162/657 - (24%)

Mouse    30 EIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESE------RKAFIVELRQLSRVNHPN 88
            ||:|.|::::||:|.|.|..|.:..:..::||||......|      |...:.|.:....:.|.|
  Fly   123 EIEYNELDIKEVIGSGGFCKVHRGYYDGEEVAIKIAHQTGEDDMQRMRDNVLQEAKLFWALKHEN 187

Mouse    89 IVKLYGACLN-PVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKAL 152
            |..|.|.||| .:|||||||.||||..:|.|..|...     .::|.:|.::|:.|||:..|.::
  Fly   188 IAALRGVCLNTKLCLVMEYARGGSLNRILAGKIPPDV-----LVNWAIQIARGMNYLHNEAPMSI 247

Mouse   153 IHRDLKPPNLLL---VAGG----TVLKICDFGTACDI-QTHMTNNKGSAAWMAPEVFEGSNYSEK 209
            ||||||..|:|:   :.|.    ..|||.|||.|.:: .|...:..|:.|||.|||...|.||:.
  Fly   248 IHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAREMYNTQRMSAAGTYAWMPPEVISVSTYSKF 312

Mouse   210 CDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVH-NGTRPPLIKNLPKPIESLMTRCWSKDPSQ 273
            .||:|:|::|||:||...|:.  |.....:.:.|. |....|:.|..|:...:||..||..||.:
  Fly   313 SDVWSYGVLLWELITGETPYK--GFDPLSVAYGVAVNTLTLPIPKTCPETWGALMKSCWQTDPHK 375

Mouse   274 RPSMEEIVKIMT---------------HLM-------------------RYFPGADEPLQYPCQY 304
            ||..:||:|.:.               |.|                   :.|...:|.|:
  Fly   376 RPGFKEILKQLESIACSKFTLTPQESFHYMQECWRKEIAGVLHDLREKEKRFQTIEEELR----- 435

Mouse   305 SDEGQ----SNSATSTGSFMDIASTNTSNKSDTNMEQ-------VPATNDTIKRLESKLLKNQAK 358
            :.|.|    .|......:.:.|...|...:....:|:       ||:     ||...|..||:..
  Fly   436 NKEEQLLRVQNEQREKANLLKIREQNLRERERVLIERELVMLQPVPS-----KRKHKKGKKNKPL 495

Mouse   359 QQS-ESG-RLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIVATAAYSK-----PKRGHRKTA 416
            |.| .:| |.::.|.|..:.:...|:..|           .||||.....|     |...|::..
  Fly   496 QISLPTGFRHTITAVRDKAEQPGSPSFSG-----------LRIVALTDGHKGKTWGPSTMHQRER 549

Mouse   417 SFGNILDVPEIVISGNGQPR-----------RRSIQDLTVTGTEPG--QVSSRSSSPSVRMITTS 468
            |.     :|. .:|| |||.           .:|..:|.....:..  ||:|.:..|.:.::..|
  Fly   550 SL-----LPS-QLSG-GQPEWPAQTSTHSSFSKSAPNLDKKQQQQNQQQVASLTPPPGLGILGGS 607

Mouse   469 GPTSEKPARS--HPWTP-----------------------DDSTDTNGSDNSIPMAYLTLDHQLQ 508
            |.....||..  :|..|                       ..:|.||.::|:........::||.
  Fly   608 GGAGGTPATPLLYPGIPIILTRPNNNNIGNCKAITTTITTTTTTTTNNNNNNNNSISANNNNQLN 672

Mouse   509 PLAPCPNSKESMAVFEQHCKMAQEYMKVQTEIALLLQRKQELVAELDQDEKDQQNTSRLVQEHKK 573
            .::...::..:          .|..:..|....::|           |:.::..|:|...|...|
  Fly   673 NISTINSNNNN----------NQTNLTSQPNTIIVL-----------QNGRNNSNSSTTSQSPAK 716

Mouse   574 LLDENKS 580
            :....:|
  Fly   717 IYHRARS 723

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Map3k7	NP_033342.1	STKc_TAK1	42..292	CDD:270960	96/299 (32%)
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809
		TyrKc	129..386	CDD:197581	96/263 (37%)
		STKc_MLK	134..389	CDD:270963	95/261 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0192
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810