Protein Alignment Map2k4 and hep

DIOPT Version :9

• Sequence 1: NP_001303296.1
• Gene: Map2k4 / 26398
• MGIID: 1346869
• Length: 408
• Species: Mus musculus
• Sequence 2: NP_001368982.1
• Gene: hep / 32256
• FlyBaseID: FBgn0010303
• Length: 1294
• Species: Drosophila melanogaster
• Alignment Length: 435
• Identity: 192/435 - (44%)
• Similarity: 240/435 - (55%)
• Gaps: 62/435 - (14%)

Mouse     2 AAPSPSGGGGSGGGGG-----TPGPIGPPAS--GHPAVSSMQGFQINFCEKAQSKRKALKLNFAN 59
            |..:||.|.||..|.|     .|.|..|.|:  |..:.||.......|...|
  Fly    62 ATHAPSLGAGSVSGSGISIAQRPAPPVPHATPFGSASASSSSSSASAFASAA------------- 113

Mouse    60 PPVKSTARFTLNPNTTGVQ--NPHIERL---------RTHSI----------------------- 90
             |...|...|..|.||.|.  .|.:..|         ||..:
  Fly   114 -PATGTFGGTYTPPTTRVSRATPTLPMLSSGPGGGLNRTRPVILPLPTPPHPPVSETDMKLKIIM 177

Mouse    91 ESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLL 155
            |.:|||.|:..| :.....|||.||::|.|..|:|.||:|..|..|:|||::|.|.:.:|.|::|
  Fly   178 EQTGKLNINGRQ-YPTDINDLKHLGDLGNGTSGNVVKMMHLSSNTIIAVKQMRRTGNAEENKRIL 241

Mouse   156 MDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLA 220
            ||||||::|.||.|||:..|...|:.|.||||||||..|||..|    :....:||:||||:|:|
  Fly   242 MDLDVVLKSHDCKYIVKCLGCFVRDPDVWICMELMSMCFDKLLK----LSKKPVPEQILGKVTVA 302

Mouse   221 TVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERID 285
            ||.||::||:...:||||:||||||:|..||||||||||||:||||.|.||.|||..||||||||
  Fly   303 TVNALSYLKDKHGVIHRDVKPSNILIDERGNIKLCDFGISGRLVDSKANTRSAGCAAYMAPERID 367

Mouse   286 PSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFI 350
            |...:  ||:|:|||||||||.||||.|.||...|:.|:.||:|:..:||.|...|...||..|.
  Fly   368 PKKPK--YDIRADVWSLGITLVELATARSPYEGCNTDFEVLTKVLDSEPPCLPYGEGYNFSQQFR 430

Mouse   351 NFVNLCLTKDESKRPKYKELLKHPFILMYEERTVEVACYVCKILD 395
            :||..||||:...||||.|||..|||.:||...|:|..:...|.|
  Fly   431 DFVIKCLTKNHQDRPKYPELLAQPFIRIYESAKVDVPNWFQSIKD 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Map2k4	NP_001303296.1	PKc_MKK4	104..394	CDD:270790	156/289 (54%)
hep	NP_001368982.1	PKc_MKK7	181..476	CDD:270791	163/302 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D470057at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920