Protein Alignment Map2k2 and lic

DIOPT Version :9

• Sequence 1: NP_075627.2
• Gene: Map2k2 / 26396
• MGIID: 1346867
• Length: 401
• Species: Mus musculus
• Sequence 2: NP_477162.1
• Gene: lic / 32257
• FlyBaseID: FBgn0261524
• Length: 334
• Species: Drosophila melanogaster
• Alignment Length: 341
• Identity: 114/341 - (33%)
• Similarity: 183/341 - (53%)
• Gaps: 59/341 - (17%)

Mouse    66 ELKDDDFERISELGAGNGGVVTKARHRPSGLIMARKLIHLEIKPAVRNQIIRELQV-LHECNSPY 129
            ::..|..|:|.:||.|..|:|.|.||:.:..::|.|.|.:.:....:::::.:|.: :...:.||
  Fly    40 DIDADSLEKICDLGRGAYGIVDKMRHKQTDTVLAVKRIPMTVNIREQHRLVMDLDISMRSSDCPY 104

Mouse   130 IVGFYGAFYSDGEISICMEHMDGGSLD----QVLKEAKRIPEDILGKVSIAVLRGLAYLREKHQI 190
            .|.||||.|.:|::.||||.| ..|||    :|.....|:.|.:|||::::|:..|.||..:.::
  Fly   105 TVHFYGAMYREGDVWICMEVM-STSLDKFYPKVFLHDLRMEESVLGKIAMSVVSALHYLHAQLKV 168

Mouse   191 MHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSF-VGTRSYMSPERL--QG--THYSVQSDI 250
            :||||||||||:|..|::|:||||:||.|:||:|.:. .|.:.||:|||:  ||  ..|.::||:
  Fly   169 IHRDVKPSNILINRAGQVKICDFGISGYLVDSIAKTIDAGCKPYMAPERIDPQGNPAQYDIRSDV 233

Mouse   251 WSMGLSLVELAIGRYPIPPPDAKELEASFGRPVVDGADGEPHSVSPRPRPPGRPISVGHGMDSRP 315
            ||:|:.::|:|.||||.                            ...|.|
  Fly   234 WSLGIGMIEMATGRYPY----------------------------DNWRTP-------------- 256

Mouse   316 AMAIFELLDYIVNEPPPKLPSGVFSSDFQEFVNKCLIKNPAERADLKLLMNHAFIKRSEGEEVDF 380
                ||.|..:|.:.||:||.|.||.:|::|:..||.|....|.:.:.|:.|:||........|.
  Fly   257 ----FEQLRQVVEDSPPRLPEGTFSPEFEDFIAVCLQKEYMARPNYEQLLKHSFIVEHLQRNTDI 317

Mouse   381 AGWLCRTLRL--KQPS 394
            :.::.|.|.|  .||:
  Fly   318 SEFVARILDLPDAQPA 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Map2k2	NP_075627.2	PKc_MEK	70..388	CDD:132946	110/327 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	282..310		2/27 (7%)
lic	NP_477162.1	PKc_MKK3_6	44..326	CDD:173729	110/328 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D688282at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2221
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.950