Protein Alignment GBX2 and ftz

DIOPT Version :9

• Sequence 1: NP_001476.2
• Gene: GBX2 / 2637
• HGNCID: 4186
• Length: 348
• Species: Homo sapiens
• Sequence 2: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Alignment Length: 406
• Identity: 88/406 - (21%)
• Similarity: 144/406 - (35%)
• Gaps: 142/406 - (34%)

Human    35 SPGHFVYT-GYPMFMPYRPVVLPP----------------------------------------- 57
            |..|:.|. ...|:..|.|..|||
  Fly     6 SQSHYSYADNMNMYNMYHPHSLPPTYYDNSGSNAYYQNTSNYQGYYPQESYSESCYYYNNQEQVT 70

Human    58 ----PP-----PPPPALPQAALQPALP--------PA-------HPHHQIPSLPTGFCSSLAQ-- 96
                ||     |||.|..:.|...|..        |:       :|..::...|..|.:::.|
  Fly    71 TQTVPPVQPTTPPPKATKRKAEDDAASIIAAVEERPSTLRALLTNPVKKLKYTPDYFYTTVEQVK 135

Human    97 -GMALTSTLMATLPGGFSASPQHQEAAAARKFAPQPLPGGG-NFDKAEALQADAEDGKGFLAKEG 159
             ..|:::.:.|      |.:|.:.:     ::...|.|... :.|..:.....::..|   .|.|
  Fly   136 KAPAVSTKVTA------SPAPSYDQ-----EYVTVPTPSASEDVDYLDVYSPQSQTQK---LKNG 186

Human   160 SLLAFSAAETVQASLVGAVRGQGKDESKVEDDPK--GKEESFSLESDVDYSSDDNLTGQAAHKEE 222
            .   |:.......:.:..:.|       :...|:  |::.|.::..::::..   :|......:.
  Fly   187 D---FATPPPTTPTSLPPLEG-------ISTPPQSPGEKSSSAVSQEINHRI---VTAPNGAGDF 238

Human   223 DPGHALEETPPSSGAAGSTTSTGKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLS 287
            :..| :|||..|        ....::|.|..:|..|.||||||||..:|::...|..||:||.||
  Fly   239 NWSH-IEETLAS--------DCKDSKRTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSLS 294

Human   288 EVQVKIWFQNRRAKWKRVK----------AG----------NANSKTGEPSRNPKIVVPIPVHVS 332
            |.|:||||||||.|.|:.:          ||          .:.:.||.||      ||:|::
  Fly   295 ERQIKIWFQNRRMKSKKDRTLDSSPEHCGAGYTAMLPPLEATSTATTGAPS------VPVPMY-- 351

Human   333 RFAIRSQHQQLEQARP 348
                  .|.|...|.|
  Fly   352 ------HHHQTTAAYP 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GBX2	NP_001476.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	59..81		9/41 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	111..139		4/28 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	179..251		11/73 (15%)
		Homeobox	250..303	CDD:306543	30/52 (58%)
ftz	NP_477498.1	FTZ	1..248	CDD:281812	42/269 (16%)
		Homeobox	257..310	CDD:278475	30/52 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810