DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ceacam10 and nrm

DIOPT Version :9

Sequence 1:	NP_031701.3	Gene:	Ceacam10 / 26366	MGIID:	1347248	Length:	265	Species:	Mus musculus
Sequence 2:	NP_001246890.1	Gene:	nrm / 40515	FlyBaseID:	FBgn0262509	Length:	2192	Species:	Drosophila melanogaster

Alignment Length:	288	Identity:	63/288 - (21%)
Similarity:	99/288 - (34%)	Gaps:	85/288 - (29%)

- Green bases have known domain annotations that are detailed below.

Mouse     2 ELASAHLHKGQVPWVGLLLTASLLTYWSPATTAQVTVEAVP------------------------ 42
            :|.|.:..||......:||..|.:|..:.....:||||..|
  Fly    70 KLHSLNWFKGDDRIAAMLLGDSNVTSVNKEFDERVTVEQNPYRLVIKDLKIADEDIYLCDTTFFI 134

Mouse    43 PNVTADN------NVLLLVHNLPQTLRVFYWYKGNSGAGHNEIGRFVTSINRSKMGLAHSGRETI 101
            |..|.||      .:.:||   |.|..|....||:.....:.:|...   .|..:....:.|.|.
  Fly   135 PEETCDNFNGYRIELRVLV---PPTEVVILDAKGDRIKNGSVVGPMQ---ERQSLKATCTVRNTR 193

Mouse   102 YSNGSLFFQSVTK-------ND--EGVYTLYM-LD---------------------QNFEITPIS 135
            ......:|:...:       :|  :|:||..: ||                     ||..:|..|
  Fly   194 PQPEVSWFRGTKRLTTYSPTHDLVDGLYTSTLELDWTLSREDLAQDIECRVKSAAIQNVTVTKFS 258

Mouse   136 VRFHVHPSLLPSLSPPTTGQVTVEAVRPNVAEGENVLLL--VHNLPRTLRAIYWYRGTT---AGE 195
            |...|.|:           .:.:..|:.:..:|..|:|.  :|. .|....:.||..||   :||
  Fly   259 VDLQVRPT-----------SIDINGVKHHTVQGSKVVLTCDIHG-ARPAVNLTWYNTTTIISSGE 311

Mouse   196 RNEIARFITASNKIILGPAHSDREIIYN 223
             |||....:.|.:...|..|:..|:|:|
  Fly   312 -NEITEVRSKSLEKSDGTFHTQSELIFN 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ceacam10	NP_031701.3	Ig_CEACAM_D1	36..140	CDD:319315	32/164 (20%)
Ceacam10	NP_031701.3	Ig_CEACAM_D1	156..260	CDD:319315	21/73 (29%)
nrm	NP_001246890.1	Ig	44..152	CDD:299845	17/81 (21%)
		Ig	176..248	CDD:299845	10/74 (14%)
		Ig	277..354	CDD:299845	20/64 (31%)
		IG_like	383..463	CDD:214653
		Ig	394..463	CDD:143165
		Ig_3	585..652	CDD:290638
		Ig	685..>719	CDD:299845
		IG_like	788..869	CDD:214653
		Ig	<811..869	CDD:299845
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000