DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GBX1 and zen2

DIOPT Version :9

Sequence 1:	NP_001092304.1	Gene:	GBX1 / 2636	HGNCID:	4185	Length:	363	Species:	Homo sapiens
Sequence 2:	NP_476794.1	Gene:	zen2 / 40827	FlyBaseID:	FBgn0004054	Length:	252	Species:	Drosophila melanogaster

Alignment Length:	129	Identity:	52/129 - (40%)
Similarity:	73/129 - (56%)	Gaps:	18/129 - (13%)

- Green bases have known domain annotations that are detailed below.

Human   246 EGAPVTAGVTAPGGKSRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQ 310
            |.||  ...|....||:|.||||:|.||:|||:|||..|||:.|.|.:|:..|.|:|.|||||||
  Fly    30 EAAP--TATTRSSEKSKRSRTAFSSLQLIELEREFHLNKYLARTRRIEISQRLALTERQVKIWFQ 92

Human   311 NRRAKWKRIKAGN-------------VSSRSGEPV-RNPKIVVPIPVHVNRFAVRSQHQQMEQG 360
            |||.|.|  |:.|             :||:|.|.: ::.:||..:..:.|.....:..:|::.|
  Fly    93 NRRMKLK--KSTNRKGAIGALTTSIPLSSQSSEDLQKDDQIVERLLRYANTNVETAPLRQVDHG 154

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GBX1	NP_001092304.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..31
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	128..265		7/18 (39%)
		Homeobox	264..317	CDD:306543	33/52 (63%)
zen2	NP_476794.1	Homeobox	46..99	CDD:278475	33/52 (63%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810