Protein Alignment HSPB8 and hspb8

DIOPT Version :10

• Sequence 1: NP_055180.1
• Gene: HSPB8 / 26353
• HGNCID: 30171
• Length: 196
• Species: Homo sapiens
• Sequence 2: NP_001005658.1
• Gene: hspb8 / 448147
• XenbaseID: XB-GENE-945643
• Length: 202
• Species: Xenopus tropicalis
• Alignment Length: 200
• Identity: 132/200 - (66%)
• Similarity: 150/200 - (75%)
• Gaps: 8/200 - (4%)

Human     1 MADGQMPFSCHYPS---RLRRDPFRDSPLSSRLLDDGFGMDPFPDDLTASWPDWALPRLSSAWPG 62
            |||.|:||:|||||   |..|||||:..|||||||:.||:.||.||||..|||||.|||:|||.|
 Frog     1 MADSQLPFTCHYPSNRHRGSRDPFREQGLSSRLLDEDFGIPPFSDDLTMDWPDWARPRLTSAWSG 65

Human    63 TLRSGMVPRG---PTATARF-GVPAEGRTPPPFPGEPWKVCVNVHSFKPEELMVKTKDGYVEVSG 123
            .||||:|..|   |...:|: |.| :.|.......:||||||||.:||||||.||||||:|||||
 Frog    66 PLRSGLVRSGMPPPVYNSRYTGYP-DARNTVANISQPWKVCVNVQTFKPEELTVKTKDGFVEVSG 129

Human   124 KHEEKQQEGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAPQVPPYSTFGESSFNNELPQ 188
            .|||:|:||||||||||||.|||.|||..|||||||||||||||||.||||:..|:.|:..|||.
 Frog   130 NHEEQQKEGGIVSKNFTKKFQLPPEVDAQTVFASLSPEGLLIIEAPVVPPYNQQGDDSYTYELPL 194

Human   189 DSQEV 193
            |.|||
 Frog   195 DPQEV 199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HSPB8	NP_055180.1	ACD_HspB8_like	80..170	CDD:107235	66/89 (74%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	176..196		8/17 (47%)
hspb8	NP_001005658.1	alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.	86..175	CDD:469641	65/89 (73%)