DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment HSPB8 and Hsp22

DIOPT Version :9

Sequence 1:NP_055180.1 Gene:HSPB8 / 26353 HGNCID:30171 Length:196 Species:Homo sapiens
Sequence 2:NP_001027114.1 Gene:Hsp22 / 3772576 FlyBaseID:FBgn0001223 Length:174 Species:Drosophila melanogaster


Alignment Length:136 Identity:43/136 - (31%)
Similarity:65/136 - (47%) Gaps:28/136 - (20%)


- Green bases have known domain annotations that are detailed below.


Human    53 LPRLSS----------AWPGTLRSGMVPRGPTATARFGVPAEGRTPPP--FPGEPWKVCVNVHSF 105
            :|||||          .|     |..:||.....||:   .|....||  ...:.:|:.::|..:
  Fly    17 MPRLSSPFHAFFHEPPVW-----SVALPRNWQQIARW---QEQEFAPPATVNKDGYKLTLDVKDY 73

Human   106 KPEELMVKTKD-GYVEVSGKHEEKQ-QEGGIVSKNFTKKIQLPA--EVDPVTVFASLSPEGLLII 166
              .||.||..| ..|.|.||.|::: ::||..|::|.::..||.  |.|.||  ::||.:|:|.|
  Fly    74 --SELKVKVLDESVVLVEGKSEQQEAEQGGYSSRHFLRRFVLPEGYEADKVT--STLSSDGVLTI 134

Human   167 EAPQVP 172
            ..|..|
  Fly   135 SVPNPP 140

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HSPB8NP_055180.1 ACD_HspB8_like 80..170 CDD:107235 30/95 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 176..196
Hsp22NP_001027114.1 IbpA 17..154 CDD:223149 43/136 (32%)
metazoan_ACD 61..138 CDD:107247 27/80 (34%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165148940
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3591
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
43.700

Return to query results.
Submit another query.