Protein Alignment GBP3 and Gbp3

DIOPT Version :10

• Sequence 1: NP_060754.2
• Gene: GBP3 / 2635
• HGNCID: 4184
• Length: 595
• Species: Homo sapiens
• Sequence 2: XP_063138992.1
• Gene: Gbp3 / 685116
• RGDID: 1597766
• Length: 790
• Species: Rattus norvegicus
• Alignment Length: 584
• Identity: 396/584 - (67%)
• Similarity: 479/584 - (82%)
• Gaps: 0/584 - (0%)

Human     1 MAPEIHMTGPMCLIENTNGELVANPEALKILSAITQPVVVVAIVGLYRTGKSYLMNKLAGKNKGF 65
            ||.|..|..|||||||..|:|.||.:||:|||||||||||:|.|||||||||||||||||:..||
  Rat     1 MALETCMPEPMCLIENVKGQLRANQKALEILSAITQPVVVIATVGLYRTGKSYLMNKLAGRKTGF 65

Human    66 SLGSTVKSHTKGIWMWCVPHPKKPEHTLVLLDTEGLGDVKKGDNQNDSWIFTLAVLLSSTLVYNS 130
            ||||||:|||.||||||||||:|.:||||||||||||||:|||||||.|||.||:|||||.||||
  Rat    66 SLGSTVQSHTTGIWMWCVPHPRKADHTLVLLDTEGLGDVEKGDNQNDCWIFALAILLSSTFVYNS 130

Human   131 MGTINQQAMDQLYYVTELTHRIRSKSSPDENENEDSADFVSFFPDFVWTLRDFSLDLEADGQPLT 195
            ||.|||||||||.||||||.|||:.|||..|..|.||:||||||||||||||.::.||.||:.||
  Rat   131 MGAINQQAMDQLQYVTELTDRIRTTSSPHSNGVEASAEFVSFFPDFVWTLRDVTVKLEKDGKMLT 195

Human   196 PDEYLEYSLKLTQGTSQKDKNFNLPRLCIRKFFPKKKCFVFDLPIHRRKLAQLEKLQDEELDPEF 260
            .||||:.|||..||||::|:|:|||||||||||||||||||..|...:||::||.|:|:|||.||
  Rat   196 ADEYLDNSLKPKQGTSEEDRNYNLPRLCIRKFFPKKKCFVFYSPTEWKKLSELESLRDDELDSEF 260

Human   261 VQQVADFCSYIFSNSKTKTLSGGIKVNGPRLESLVLTYINAISRGDLPCMENAVLALAQIENSAA 325
            :||.|:|||:|||:||.|.|.|||:|||.|||.||||||:|||.|.||||||||||||::|||||
  Rat   261 LQQAANFCSFIFSSSKAKRLPGGIQVNGARLEKLVLTYISAISSGHLPCMENAVLALAKVENSAA 325

Human   326 VQKAIAHYDQQMGQKVQLPAETLQELLDLHRVSEREATEVYMKNSFKDVDHLFQKKLAAQLDKKR 390
            :||||.||||||.||||||.:||||||||||..||||.:::::.||||.||.|:|.|.|||:||.
  Rat   326 IQKAITHYDQQMCQKVQLPTDTLQELLDLHRTCEREAKDIFLRTSFKDEDHSFKKDLLAQLEKKW 390

Human   391 DDFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGGYCLFIQKLQDLEKKYYEEPRKGIQA 455
            :....:|...||.|||.||:.||.||||.|..|.||:||||.|:::|.::|:|||.:||:|||||
  Rat   391 NGINNENMNKSSTRCSELLRDIFGPLEEAVINGAYSQPGGYLLYVEKREELKKKYLQEPKKGIQA 455

Human   456 EEILQTYLKSKESVTDAILQTDQILTEKEKEIEVECVKAESAQASAKMVEEMQIKYQQMMEEKEK 520
            |||||.||:|..:|.:|:||.||.||.|:||||||..|||||||:.:::||::.|:.|||:|||:
  Rat   456 EEILQEYLQSNAAVAEALLQRDQALTVKQKEIEVERAKAESAQATVRILEEVEKKHAQMMKEKER 520

Human   521 SYQEHVKQLTEKMERERAQLLEEQEKTLTSKLQEQARVLKERCQGESTQLQNEIQKLQKTLKKK 584
            .:||.|:||||.|||||||::||||:.|..|||||.|::||..:.||.:|:||||.:::..::|
  Rat   521 CHQERVRQLTENMERERAQVVEEQERILNLKLQEQKRLIKEGLKEESLRLKNEIQLMEQRNREK 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GBP3	NP_060754.2	GTPase domain (Globular). /evidence=ECO:0000250|UniProtKB:P32455	1..309		227/307 (74%)
		GBP	18..280	CDD:460516	195/261 (75%)
		GBP_C	282..574	CDD:460721	185/291 (64%)
Gbp3	XP_063138992.1	None