Protein Alignment GBP3 and LOC100488013

DIOPT Version :10

• Sequence 1: NP_060754.2
• Gene: GBP3 / 2635
• HGNCID: 4184
• Length: 595
• Species: Homo sapiens
• Sequence 2: XP_012823014.1
• Gene: LOC100488013 / 100488013
• XenbaseID: XB-GENE-29079035
• Length: 657
• Species: Xenopus tropicalis
• Alignment Length: 584
• Identity: 296/584 - (50%)
• Similarity: 401/584 - (68%)
• Gaps: 11/584 - (1%)

Human     7 MTGPMCLIENTNG-ELVANPEALKILSAITQPVVVVAIVGLYRTGKSYLMNKLAG---KNKGFSL 67
            |..|||||||..| ||..|.|||:||..||||||||||||.||||||||||.|||   ::.||:|
 Frog    34 MGEPMCLIENKEGEELTVNQEALEILLEITQPVVVVAIVGKYRTGKSYLMNILAGARNEHSGFAL 98

Human    68 GSTVKSHTKGIWMWCVPHPKKPEHTLVLLDTEGLGDVKKGDNQNDSWIFTLAVLLSSTLVYNSMG 132
            ||||:|.||||||||||||.|..||||||||||||||:|||::||:|||:||:||||||||||||
 Frog    99 GSTVRSKTKGIWMWCVPHPTKKGHTLVLLDTEGLGDVEKGDSKNDAWIFSLAILLSSTLVYNSMG 163

Human   133 TINQQAMDQLYYVTELTHRIRSKSSPDENEN-EDSADFVSFFPDFVWTLRDFSLDLEADGQPLTP 196
            ||:|||||.|:||||||.||:.||...:.|: :::.:|..|||.|:|.:|||:|.||.||.|:|.
 Frog   164 TIDQQAMDNLHYVTELTERIKVKSHEGKAEDMDETGEFKRFFPSFIWCVRDFTLQLEKDGVPITE 228

Human   197 DEYLEYSLKLTQGTSQKDKNFNLPRLCIRKFFPKKKCFVFDLPIHRRKLAQLEKLQDEELDPEFV 261
            |:||..:|:|.:|..:|.:::||||.|||.:|...||||||.|..:..|.:||:||:.||:.|||
 Frog   229 DQYLMDALELKRGVGKKVQDYNLPRQCIRHYFHSHKCFVFDRPASKADLQRLEELQESELELEFV 293

Human   262 QQVADFCSYIFSNSKTKTLSGGIKVNGPRLESLVLTYINAISRGDLPCMENAVLALAQIENSAAV 326
            .:...|||:|..:...|||.||..|.|..|.:|...|..||..|.:|||||||.|||..|||.||
 Frog   294 DKAITFCSFINQHCNAKTLVGGTIVTGRTLGNLTDLYTEAIRSGSIPCMENAVKALADRENSRAV 358

Human   327 QKAIAHYDQQMGQKV-QLPAETLQELLDLHRVSEREATEVYMKNSFKDVDHLFQKKLAAQLDKKR 390
            |:|:..|:::|.::: :.|.||.:|.|.:|:..|:|||:|:|..||||.:..:|.:|..:|.:::
 Frog   359 QEALTKYEEEMSKQIAKFPTETQEEFLSIHQECEKEATKVFMGLSFKDENGQYQNQLIDELAEEK 423

Human   391 DDFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGGYCLFIQKLQDLEKKYYEEPRKGIQA 455
            ..:...|:|.|:.:|.|:||.:...||.|:..|.:||||||..||.:...|..||.:...||::|
 Frog   424 SKYSLHNEEESAKKCKAILQKLNESLEREISEGKFSKPGGYTQFISEKNLLVDKYNKTKGKGVKA 488

Human   456 EEILQTYLKSKESVTDAILQTDQILTEKEKEIEVECVKAESAQASAKMVEEMQIKYQQMMEEKEK 520
            .||::.:|..|:.|.::|||.||.||..|||||.:..:.|:|:...::|||...:.::.||.::|
 Frog   489 PEIIEEFLNEKKIVEESILQADQSLTATEKEIEEQRARTETAEREKQIVEENNRRLEKDMENQKK 553

Human   521 SYQEHVKQLTEKMERERAQLLEEQEKTLTSKLQEQARVLKERCQGESTQLQNEIQKLQKTLKKK 584
            |.::|.|.|.||||.||.:|:|:.|..:..||:|...:||     :....|:||.|.|..|.|:
 Frog   554 SLEDHKKMLEEKMEEERKKLMEQNEWMIKEKLKEADELLK-----KGFDAQSEIVKYQSRLLKE 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GBP3	NP_060754.2	GTPase domain (Globular). /evidence=ECO:0000250|UniProtKB:P32455	1..309		183/306 (60%)
		GBP	18..280	CDD:460516	163/266 (61%)
		GBP_C	282..574	CDD:460721	117/292 (40%)
LOC100488013	XP_012823014.1	GBP	47..312	CDD:460516	162/264 (61%)
		GBP_C	314..601	CDD:460721	117/291 (40%)